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Laboratory guide to the methods in biochemical genetics / [edited by] Nenad Blau, Marinus Duran, K. Michael Gibson ; foreword by C.R. Scriver.

Ebook Central Academic Complete Available online

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Format:
Book
Contributor:
Blau, N. (Nenad), 1946-
Duran, Marinus.
Gibson, Kenneth Michael, 1955-
Language:
English
Subjects (All):
Metabolism, Inborn errors of--Diagnosis--Laboratory manuals.
Metabolism, Inborn errors of.
Biochemical genetics--Laboratory manuals.
Biochemical genetics.
Physical Description:
1 online resource (882 p.)
Edition:
1st ed. 2008.
Place of Publication:
Berlin ; London : Springer, c2008.
Language Note:
English
Summary:
Suitable for those interested in laboratory diagnosis, this book describes laboratory methodology for diagnosing inborn errors of metabolism.
Contents:
Laboratory Strategies in Biochemical Genetics
Quality Control and Quality Assurance in the Biochemical Genetic Laboratory
Simple Metabolic Screening Tests
Lactate, Pyruvate, Acetoacetate and 3-Hydroxybutyrate
Amino Acids
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine
GABA, Homocarnosine, and ?-Alanine
Pipecolic Acid
Organic Acids
Acylcarnitines, Including In Vitro Loading Tests
Plasmalogens and Polyunsaturated Fatty Acids
Very-Long-Chain Fatty Acids and Phytanic Acid
Oxalate, Glycolate, Glycerate, Sulfate, and Citrate
Glycerol and Glycerol Phosphates
Biotinidase
Mitochondrial Respiratory Chain
Mucopolysaccharides
Oligosaccharides
Sialic Acid
Glycosphingolipids
Congenital Disorders of Glycosylation
Enzymes and Metabolites of Carbohydrate Metabolism
Polyols
Diagnosis of Inherited Defects of Cholesterol Biosynthesis
Lipoproteins
Genetic Disorders of Steroid Metabolism Diagnosed by Mass Spectrometry
Bile Acids
Pterins and Related Enzymes
Biogenic Amines
Folates
Screening for Disorders of Purine and Pyrimidine Metabolism Using HPLC-Electrospray Tandem Mass Spectrometry
Creatine and its Metabolites
Porphyrins, Porphobilinogen, and ?-Aminolevulinic Acid
Trimethylaminuria
A Tandem Mass Spectrometry Primer for Metabolite Disease Detection
Molecular Genetics: Mutation Analysis in the Diagnosis of Metabolic Disorders.
Notes:
Description based upon print version of record.
Includes bibliographical references and index.
ISBN:
1-281-49242-6
9786611492427
3-540-76698-7
OCLC:
272298711

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