Beyond regulations : ethics in human subjects research / edited by Nancy M.P. King, Gail E. Henderson, Jane Stein.

Format:

Book

Contributor:

King, Nancy M. P.

Henderson, Gail, 1949-

Stein, Jane.

Series:

Studies in social medicine.

Studies in social medicine

Language:

English

Subjects (All):

Human experimentation in medicine--Moral and ethical aspects--Case studies.

Human experimentation in medicine.

Medical ethics.

Physical Description:

1 online resource (293 p.)

Edition:

1st ed.

Place of Publication:

Chapel Hill : University of North Carolina Press, c1999.

Language Note:

English

Summary:

Across a broad range of disciplines--in medicine, social science, and the humanities--researchers, scholars, teachers, and administrators increasingly are looking for new ways to approach ethical issues in research with human subjects. Questions about how relationships between funders and researchers should affect research design, for example, or whether the potential benefits of research can outweigh the importance of its subjects' interests are inadequately addressed by the prevailing, regulation-based research ethics paradigm. This book constitutes a reexamination of research ethics. It combines case studies and commentaries by a multidisciplinary group of scholars and researchers to explore such topics as informed consent, conflict of interest, confidentiality, and research on illegal behavior. All human subjects research takes place within complex social, cultural, and political contexts, the contributors argue. Increased consideration of the relationships between researchers and their subjects, funders, and institutions within these contexts will facilitate research that is sensitive and responsible as well as scientifically fruitful. Beyond Regulations features a keynote essay by Ruth Macklin. Other contributors are Marcela Aracena Alvarez, Jorge Bal an, B. Susan Bauer, Alan F. Benjamin, Lynn Blanchard, Allan M. Brandt, J. Pat Browder, Barbara Entwisle, Sue E. Estroff, Ren ee C. Fox, Lara Freidenfelds, Gail E. Henderson, Nancy M. P. King, Loretta M. Kopelman, Ernest N. Kraybill, Barry M. Popkin, Silvina Ramos, Desmond K. Runyan, Jane Stein, Ronald P. Strauss, Keith A. Wailoo, and Cynthia Waszak. Across a broad range of disciplines--in biomedicine, the social sciences, and the humanities--researchers, scholars, administrators, and teachers increasingly struggle with questions of ethics in research with human subjects. All research takes place in complex social, cultural, political, and economic contexts; yet the prevailing principle-based research ethics paradigm does not adequately account for them. This book reexamines research ethics using a new relationships paradigm. Through in-depth cases, commentaries, and essays, a multidisciplinary group of scholars and researchers addresses informed consent, conflict of interest, confidentiality, and other issues, considering questions like: What relationships should researchers have with their subjects' communities? When researchers and subjects have different views about research, who should have control? How should relationships between funders and researchers affect research design? Can research be so potentially beneficial that its importance outweighs the interests of subjects? Examining the relationships between researchers and subjects, communities, funders, and institutions--including considerations of authority and voice--can facilitate human subjects research that is morally sensitive and responsible as well as scientifically fruitful.

Contents:

""Contents""; ""Foreword""; ""Acknowledgments""; ""Introduction. Relationships in Research: A New Paradigm""; ""A Brief History: Images and Ethics of Human Subjects Research""; ""Problem Cases""; ""Moral Principles""; ""Domestic and International Research: Do the Regulations Apply?""; ""Policy: The Regulations""; ""CIOMS Guidelines""; ""A Paradigm Shift: Are the Regulations Enough?""; ""Toward a New Analysis""; ""Notes""; ""Keynote Essay""; ""Introduction""; ""Is Ethics Universal?: Gender, Science, and Culture in Reproductive Health Research (Ruth Macklin)""

""The Universality of Ethical Principles Governing Research""""Research Ethics beyond Regulations""; ""Conclusion""; ""Notes""; ""Case 1. Contracts and Covenants""; ""Introduction""; ""Contract and Covenant in Curacao: Reciprocal Relationships in Scholarly Research (Alan F. Benjamin)""; ""Setting""; ""Issues and Motivations""; ""Discussion""; ""Notes""; ""Commentary 1. Contract and Covenant in Ethnographic Research (Renee C. Fox)""; ""Note""; ""Commentary 2. The Gaze of Scholars and Subjects: Roles, Relationships, and Obligations in Ethnographic Research (Sue E. Estroff)""; ""Note""

""Case 2. Community-based HIV Research""""Introduction""; ""Community Assessment and Perceptions: Preparation for HIV Vaccine Efficacy Trials (Lynn Blanchard)""; ""Introduction""; ""Description of Project""; ""Location of Project""; ""Community Advisory Board""; ""Note""; ""Commentary 1. Community Advisory Board-Investigator Relationships in Community-Based HIV/AIDS Research (Ronald P. Strauss)""; ""Introduction""; ""Ethical and Social Issues""; ""The Rationale of Research""; ""The Uses of the Research""

""Commentary 2. Research Partnerships and People ""at Risk"": HIV Vaccine Efficacy Trials and African American Communities (Keith A. Wailoo)""""Note""; ""Case 3. Corporate Sponsorship of Research""; ""Introduction""; ""Truth-in-Funding: Studying the Infant-feeding Controversy with Industry Support (Barry M. Popkin)""; ""Introduction""; ""History of the Infant-Feeding Project at UNC-CH""; ""What Did We Study?""; ""Why Not NIH?""; ""Ethical Implications of the Issues""; ""The Current Situation Regarding Industry Sponsorship of Research""; ""Personal Conclusions""; ""Funding Source Biases""

""Openness about Funding Sources""""Postmortem""; ""Notes""; ""Commentary 1. Bias and Conflicts of Interest in Science: Controversial Industry Funding of Infant-feeding Studies (Loretta M. Kopelman)""; ""The Scientific Framework""; ""The Framework Assumptions of Advocacy""; ""The Framework Assumptions of Business""; ""Multiple Frameworks""; ""Notes""; ""Commentary 2. Context and Community: Assessing the Ethics of Industry-Funded Research (Allan M. Brandt and Laura Freidenfelds)""; ""Contexts""; ""Interests""; ""Policy""; ""Conclusions""; ""Case 4. Risk and Trust in Abortion Research""

""Introduction""

Notes:

Description based upon print version of record.

Includes bibliographical references (p. [258]-271) and index.

ISBN:

9798890867780

9780807876060

0807876062

OCLC:

62153627