Cancer biomarkers : the promises and challenges of improving detection and treatment / Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment, Institute of Medicine of the National Academies ; Sharyl J. Nass and Harold L. Moses, editors.

Format:

Book

Contributor:

Nass, Sharyl J.

Moses, Harold L.

National Academies Press (U.S.)

Institute of Medicine (U.S.). Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment.

Language:

English

Subjects (All):

Tumor markers.

Cancer--Diagnosis.

Cancer.

Cancer--Treatment.

Physical Description:

1 online resource (252 p.)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academies Press, c2007.

Language Note:

English

Summary:

Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and detection, to improve the drug development process, and to enhance the effectiveness and safety of cancer care by allowing physicians to tailor treatment for individual patients-an approach known as personalized medicine. However, progress overall has been slow, despite considerable effort and investment, and there are still many challenges and obstacles to overcome before this paradigm shift in oncology can become a reality.

Contents:

""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Boxes, Figure, and Tables""; ""Summary""; ""1 Introduction""; ""2 Methods, Tools, and Resources Needed to Discover and Develop Biomarkers""; ""3 Guidelines, Standards, Oversight, and Incentives Needed for Biomarker Development""; ""4 Methods and Process Needed for Clinical Adoption and Evaluation of Biomarker-Based Diagnostics""; ""Acronyms and Glossary""

""Appendix: Developing Biomarker-Based Tools for Cancer Screening, Diagnosis,and Treatment: The State of the Science, Evaluation, Implementation, and Economics, Workshop Summary

Margie Patlak and Sharyl Nass, Rapporteurs""

Notes:

Description based upon print version of record.

Includes bibliographical references.

ISBN:

9786610844333

9780309133999

0309133998

9781280844331

1280844337

9780309667111

0309667119

OCLC:

923276655