The regulatory genome : gene regulatory networks in development and evolution / Eric H. Davidson.

Format:

Book

Author/Creator:

Davidson, Eric H., 1937-2015.

Language:

English

Subjects (All):

Genetic regulation.

Developmental genetics.

Physical Description:

1 online resource (303 p.)

Edition:

1st ed.

Place of Publication:

Amsterdam ; Boston : Elsevier/Academic Press, c2006.

Language Note:

English

Summary:

Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networ

Contents:

Front cover; Title page; Copyright page; Table of contents; Preface; 1 The ""Regulatory Genome"" for Animal Development; THE FRAMEWORK; THE REGULATORY APPARATUS ENCODED IN THE DNA; THE REGULATORY DEMANDS OF DEVELOPMENT; EVOLUTION, DEVELOPMENT, AND THE REGULATORY GENOME; 2 cis-Regulatory Modules, and the Structure/Function Basis of Regulatory Logic; GENERAL OPERATING PRINCIPLES; MODULARITY, A GENERAL PROPERTY OF GENOMIC REGULATORY CONTROL UNITS; INSIDE THE cis-REGULATORY MODULE: LOGIC PROCESSING AND INPUT/OUTPUT RELATIONS; cis-REGULATORY DESIGN

CONTROL BY SEQUENCE-SPECIFIC INTERACTIONS AMONG DISTANT cis-REGULATORY ELEMENTS3 Development as a Process of Regulatory State Specification; DEVELOPMENTAL PROCESSES OF THE PREGASTRULAR EMBRYO; COMPARATIVE VIEW OF EMBRYONIC PROCESSES, AND THE ORGANIZATION OF THE UNDERLYING GENE; REGULATORY STATE AND NETWORK CIRCUITRY IN BUILDING ADULT BODY PARTS; BODY PLAN DEVELOPMENT AND THE ORGANISM; 4 Gene Regulatory Networks for Development: What They Are, How They Work, and What They Mean; GENERAL STRUCTURAL PROPERTIES OF DEVELOPMENTAL GENE REGULATORY NETWORKS

GENE REGULATORY NETWORKS FOR EMBRYONIC DEVELOPMENTNETWORKS THAT CONTROL CONSTRUCTION OF COMPONENTS OF ADULT BODY PARTS; CONCLUDING REMARKS; 5 Gene Regulatory Networks: The Roots of Causality and Diversity in Animal Evolution; EVOLUTIONARY IMPLICATIONS OF THE STRUCTURE AND FUNCTION OF GENE REGULATORY NETWORKS; BILATERIAN KERNELS, PREDICTED AND REAL; SUBPHYLETIC EVOLUTION OF BILATERIAN BODY PLANS: box GENES AS SOURCES OF LABILE NETWORK INPUT/OUTPUT SWITCHES; METAZOAN ORIGINS AND GENE NETWORKS BEFORE KERNELS; References; Figure Citations; Index

Notes:

Description based upon print version of record.

Includes bibliographical references (p. 241-273) and index.

ISBN:

9786610641321

9781280641329

1280641320

9780080455570

0080455573

OCLC:

476000251