Secretory systems and toxins / edited by Michal Linial, Alfonso Grasso and Philip Lazarovici.

Format:

Book

Contributor:

Grasso, Alfonso.

Lazarovici, Philip.

Linial, Michal.

Series:

Cellular and molecular mechanisms of toxin action ; v. 2.

Cellular and molecular mechanisms of toxin action, 1026-4078 ; v. 2

Language:

English

Subjects (All):

Secretion.

Toxins.

Neurotoxic agents.

Physical Description:

1 online resource (500 p.)

Edition:

1st ed.

Place of Publication:

Amsterdam : Harwood Academic Publishers, 1998.

Language Note:

English

Summary:

This volume deals with the relationships between toxins and one of the most fundamental processes in any living cell - the secretory cycle. The reader will find up-to-date information on secretion, generated by experts in this fast evolving field. In the last decade extensive molecular and cellular studies have exposed the molecular similarity among most known secretory systems. In this book secretion is discussed from its basic mode found in yeast up to its most sophisticated version in neurotransmitter release in nerve terminals. A comprehensive view on the mode of action of toxins which blo

Contents:

Book Cover; Title; Contents; Preface to the Series; Preface; Contributors; Synaptic Vesicle Proteins: A Molecular Study; Synaptic Vesicle Proteins: A Genetic Approach; Dissection of the Secretory Machinery; Vesicular Trafficking on the Late Secretory Pathway in the Budding Yeast, S. Cerevisiae: Yeast as a Genetic Tool in Which to Explore Protein Export; Regulatory Roles for Lipids in Vesicle Trafficking and Secretion; Fusion Proteins and the Fusion Events; Tetanus Toxin as a Valuable Pharmacological Tool for Studying Polysialogangliosides in Neuronal Signal Transduction

Molecular Mechanisms of the Action of Clostridium Botulinum Type B Neurotoxin-Latrotoxin Receptors; Neurotoxins and Safety-Latches of the Secretory Process; Bacterial Neurotoxins in Invertebrates: Aplysia and the Deciphering of the Mode of Action of Clostridial Neurotoxins; Chromaffin Cells as a Secretory System: The Use of Neurotoxins; External Ions and -Latrotoxin Action; Botulinum Neurotoxins and their Substrates; Clostridial Neurotoxins as Enzymes: Structure and Function; Purification, Function and Selectivity in -Latrotoxin

Neurotoxins, Cytoskeletons and Calcium Channels: Functional Studies at Mammalian Synapses Formed in CultureThe Synapsins and Neurotransmission; Morphological Studies of the Secretory Machinery Using Neurotoxin Probes; Membrane Fusion Protein Annexin VII: A Ca2+-Activated GTPase Target for Mastoparan in Secreting Chromaffin Cells; Glossary; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-04-019029-4

0-429-07777-7

1-4822-8342-5

1-280-07992-4

9786610079926

0-203-30429-2

9780429077777

OCLC:

475891948