Hematopoietic stem cell transplantation / edited by Anthony D. Ho, Rainer Haas, Richard E. Champlin.

Format:

Book

Contributor:

Ho, Anthony.

Haas, R. (Rainer), 1955-

Champlin, Richard.

Language:

English

Subjects (All):

Hematopoietic stem cells--Transplantation.

Hematopoietic stem cells.

Physical Description:

1 online resource (609 p.)

Edition:

1st ed.

Place of Publication:

New York : Marcel Dekker, c2000.

Language Note:

English

Summary:

This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. <BR>Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immun

Contents:

Preface; Contents; Contributors; Thrombopoietin; Preclinical Biology and Potential Clinical Utility of flt3 Ligand; Stem Cell Factor; Cytokine Modulation of Hematopoietic Stem Cell Phenotype; Homing and Self-Renewal of Hematopoietic Stem Cells; Requirements for Hematopoietic Stem Cell Engraftment and Graft Engineering; Ins and Outs of Hematopoietic Stem Cells; Cell Signaling by Adhesion Receptors in Normal and Leukemic Hematopoiesis; Detection of Infrequent Cells in Blood and Bone Marrow by Flow Cytometry; Human/Sheep Hematopoietic Chimeras; Canine Models for Transplantation and Gene Therapy

Murine Model of In Utero TransplantationCD34 Selection Using Immunomagnetic Beads; Autologous and Allogeneic Transplantation with Blood CD34+ Cells; Using Allogeneic Graft Engineering to Improve Long-Term Survival; Detection and Significance of Minimal Residual Disease from Solid Tumor Malignancies in Stem Cell Autografts; Stem Cell Isolation with Immunomagnetic Beads and Tumor Cell Contamination; CD34 Cell Culture; Critical Parameters Influencing the Expansion and Differentiation of Cultured Human CD34+ Cells; Mobilization of Peripheral Blood Stem Cells from Normal Donors

Innovative Approaches for Allogeneic Blood and Marrow Transplantation for Treatment of Hematological MalignanciesPeripheral Blood Stem Cells for Allogeneic Transplantation; Mechanisms of Cure of Acute Myeloid Leukemia with Allogeneic Transplantation; Late Complications of Hematopoietic Stem Cell Transplantation; Prevention of Acute Graft-Versus-Host Disease by Delayed or Selected Lymphocyte Add Back; Blood Stem Cell Versus Bone Marrow Transplantation; Autologous Peripheral Blood Stem Cell Collection and Engraftment; Stem Cell Transplantation for Hodgkin's Disease

Stem Cell Transplantation for Multiple Myeloma-10 Years LaterHigh-Dose Therapy for Primary and Metastatic Breast Cancer; Gene Therapy Using Hematopoietic Stem Cells; Gene Therapy for Human Immunodeficiency Virus Infection Using Stem Cell Transplantation; Autografting Followed by Low-Intensity Conditioning Regimen for Allografting; Development of Retroviral Vectors that Target Hematopoietic Stem Cells; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-04-017534-1

0-429-16445-9

1-280-19132-5

9786610191321

0-203-90803-1

0-8247-4181-1

9780429164453

OCLC:

71335387