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Hormonal regulation of farm animal growth / K.L. Hossner.

Ebook Central Academic Complete Available online

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Format:
Book
Author/Creator:
Hossner, K. L. (Kim L.)
Language:
English
Subjects (All):
Growth regulators.
Hormones.
Livestock--Growth--Regulation.
Livestock.
Physical Description:
1 online resource (231 p.)
Edition:
1st ed.
Place of Publication:
Wallingford, Oxfordshire, UK ; Cambridge, MA : CABI Pub., c2005.
Language Note:
English
Summary:
This book describes the cellular and molecular mechanisms that are involved with the regulation of cell and tissue growth, including development and body composition. The emphasis is on circulating hormones, local growth factors and gene transcription factors which regulate growth and differentiation of skeletal muscle, bone and adipose tissue.
Contents:
Intro
Contents
1 Whole Animal Growth
Measuring Animal Growth
Embryonic and Fetal Growth
Growth Curves
Genetics, Nutrition and Environmental Effects on Whole Animal Growth
Genetics
Nutrition
Environmental factors
2 Cellular and Molecular Biology
Prokaryotic and Eukaryotic Organisms
Eukaryotic cell organelles
The Cell Cycle
The Central Dogma of Cell Biology
Eukaryotic genes
Ribonucleic Acid
Messenger RNA and translation of protein
RNA polymerases
Regulation of gene transcription
Transcriptional control of specific genes
Transcription factors
Biotechnology and Genetic Engineering
Transgenic Animals and their Potential
Identifying, Isolating and Transferring Genes
Homologous recombination, gene targeting and gene knockouts
3 The Endocrine System
Control of Pituitary Hormone Secretion
Hormone Receptors
Effector Molecules, Transducers and Second Messengers
4 Development of Muscle, Skeletal System and Adipose Tissue
Embryonic Development and Cell Differentiation
Cell Proliferation and Differentiation
The Skeletal System and Bone Growth
Types of Bones and Gross Anatomy
Bone Cells and Bone Matrix Formation
Osteoclasts and bone resorption
Regulation of osteoclast function
The Epiphyseal Plate
Skeletal Muscle Development
Embryonic formation of skeletal muscle
Skeletal muscle satellite cells
Myofilaments, Myofibrils and Sarcomeres
Sarcomeric proteins: actin, myosin and titin
Myofibres and muscle contraction
Skeletal Muscle Fibre Types
Skeletal muscle protein turnover
The formation of multinucleated skeletal muscle cells
Adipose Tissue Growth and Development
Brown adipose tissue
White adipose tissue
Adipose tissue development
Adipose tissue growth: hyperplasia vs hypertrophy
Lipogenesis and Lipolysis.
5 Growth Hormone and Insulin-like Growth Factors
The GH Molecule
Control of GH secretion
GH receptors
Metabolic actions of GH
Excess and inadequate GH: giants and dwarfs
IGFs or Somatomedins
Discovery of the IGFs
IGF genes and molecules
IGF receptors
IGF-binding proteins
Metabolic effects of the IGFs
Effects of the IGFs on animal growth
Modification of the somatomedin hypothesis
Effects of GH on Farm Animal Production
GH and the development of transgenic animals
6 Calcium Homeostasis and Regulation of Bone Growth
Hormonal Regulation of Calcium Homeostasis
Parathyroid hormone
1,25-Dihydroxy vitamin D[sub(3)]
Biological actions of 1,25-dihydroxy vitamin D[sub(3)]
Calcitonin
Regulation of Bone Growth and Development
The hedgehogs and early skeletal differentiation
Regulation of bone growth and differentiation by hormones
Growth factors and bone
FGF
PDGF
Transforming growth factor-&amp
#946
Bone morphogenetic proteins
7 Hormones, Growth Factors and Skeletal Muscle
Experimental Systems to Study Myogenesis
Myogenic cell systems
Muscle Regulatory Factors (MRFs)
Effects of the MRFs on muscle development
Regulation of MRF expression
Growth Factors Affecting Muscle Growth
IGFs
Myostatin
TGF-&amp
BMPs
Hepatocyte growth factor
Hormones regulating muscle growth
8 Hormones, Growth Factors and Adipose Tissue
Cell Systems Used to Study Adipogenesis
Transcription Factors and Adipogenesis
PPARs
C/EBPs
ADD1/SREBP1
Nuclear co-activators and co-repressors: fine-tuning the adipogenic response
Hormones and Growth Factors Affecting Preadipocytes and Adipocytes
Insulin
GH and the IGFs
Glucocorticoids
Prostaglandins and cAMP
Negative Regulators of Adipose Differentiation.
Adipose tissue as an endocrine organ
9 Steroids and Animal Growth
Oestrogens and Ruminant Growth
Oestrogens and Non-ruminants
Androgens and Ruminant Growth
Mechanism of Action of Steroids in Ruminant Growth
Androgen mechanisms of action
10 Catecholamines, Beta-agonists and Nutrient Repartitioning
The Autonomic Nervous System and the Adrenal Medulla
Adrenergic Receptors
&amp
-Adrenergic agonists
Effects of &amp
-adrenergic agonists on growth and body composition
11 Leptin, Body Composition and Appetite Control
Theories on the Short-term Regulation of Food Intake
The Long-term Regulation of Food Intake - the Lipostat Theory
The Discovery of Leptin
The leptin gene and molecule
Leptin receptors and binding proteins
Biological actions of leptin
Effects of leptin on reproduction
Direct peripheral effects of leptin
Regulation of leptin concentrations
Significance of leptin to animal production
Appetite-inducing (Orexigenic) Peptides of the Hypothalamus
Index
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
Z.
Notes:
Bibliographic Level Mode of Issuance: Monograph
Includes bibliographical references and index.
ISBN:
1-280-73558-9
9786610735587
1-84593-090-8
OCLC:
228146904
Publisher Number:
9780851990804

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