Electrochemical sensors, biosensors and their biomedical applications / edited by Xueji Zhang, Huangxian Ju, Joseph Wang.

Format:

Book

Contributor:

Zhang, Xueji.

Ju, Huangxian.

Wang, Joseph, 1948-

Language:

English

Subjects (All):

Electrochemical analysis.

Biosensors.

Physical Description:

1 online resource (625 p.)

Edition:

1st ed.

Place of Publication:

Amsterdam ; Boston : Academic Press, c2008.

Language Note:

English

Summary:

This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field - including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many special

Contents:

Front cover; Electrochemical sensors, biosensors and their biomedical applications; Copyright page; Contents; List of contributors; Preface; Chapter 1 Nitric oxide (NO) electrochemical sensors; 1.1 Introduction; 1.1.1 Significance of nitric oxide in life science; 1.1.2 Methods of measurement of nitric oxide in physiology; 1.1.3 Advantages of electrochemical sensors for determination of NO; 1.2 Principles of determination of NO by electrochemical sensors; 1.3 Fabrication of electrodes for NO determination; 1.3.1 Clark type NO electrodes; 1.3.2 Modified carbon fiber NO microelectrodes

1.3.3 Integrated NO microelectrodes 1.3.4 Other NO electrodes; 1.4 Calibration of NO electrodes; 1.4.1 Calibration using an NO standard solution; 1.4.2 Calibration based on decomposition of SNAP; 1.4.3 Calibration based on chemical generation of NO; 1.5 Characterization of NO electrodes; 1.5.1 Sensitivity and detection limit; 1.5.2 Selectivity; 1.5.3 Response time; 1.5.4 Effect of temperature and pH on NO electrodes; 1.6 Selected applications of NO electrodes; 1.7 Concluding remarks and other directions; 1.8 Acknowledgments; 1.9 References; Chapter 2 Biosensors for pesticides; 2.1 Introduction

2.1.1 Need for pesticide biosensors 2.1.2 Developments in pesticide biosensors; 2.1.3 Thrust areas for pesticide biosensors; 2.2 Biocatalysts used in pesticide biosensors; 2.2.1 Enzymes used in pesticide biosensors and their features; 2.2.2 Immobilization methods used in pesticide biosensors design; 2.3 Enzyme-based biosensors construction; 2.3.1 Pesticides measuring principles; 2.3.2 Inhibition-based biosensors; 2.3.3 Catalysis-based biosensors; 2.3.4 Flow injection biosensors; 2.3.5 Enzyme reactivation; 2.4 Pesticide immunosensors; 2.4.1 Detection methods for pesticide immunosensors

2.4.2 Immunosensors for pesticides 2.4.3 Regeneration of pesticide immunosensors; 2.5 Whole cell and tissue-based pesticide biosensors; 2.6 Major interfering compounds and sample pretreatment; 2.7 Conclusions; 2.8 Acknowledgments; 2.9 References; Chapter 3 Electrochemical glucose biosensors; 3.1 Introduction; 3.2 Forty years of progress; 3.3 First-generation glucose biosensors; 3.3.1 Redox interferences; 3.3.2 Oxygen dependence; 3.4 Second-generation glucose biosensors; 3.4.1 Electron transfer between GOx and electrode surfaces; 3.4.2 Use of artificial mediators

3.4.3 Attachment of electron-transfer relays 3.5 In-vitro glucose testing; 3.6 Continuous real-time in-vivo monitoring; 3.6.1 Requirements; 3.6.2 Subcutaneous monitoring; 3.6.3 Towards non-invasive glucose monitoring; 3.7 Conclusions and outlook; 3.8 References; Chapter 4 New trends in ion-selective electrodes; 4.1 Introduction; 4.1.1 State-of-the-art; 4.1.2 Most important biomedical applications of ion-selective electrodes; 4.2 Classical ion-selective electrodes; 4.2.1 Understanding of the operational principles; 4.2.2 Response characteristics: selectivity and detection limits

4.2.3 Reference electrodes

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-05551-4

9786611055516

0-08-055489-X

OCLC:

476129102