Primate models of children's health and developmental disabilities / [edited by] Thomas M. Burbacher, Gene P. Sackett, Kimberly S. Grant.

Format:

Book

Contributor:

Burbacher, Thomas.

Grant, Kimberly S.

Sackett, Gene P.

Language:

English

Subjects (All):

Pediatrics.

Child development deviations.

Animal models in research.

Physical Description:

1 online resource (480 p.)

Edition:

1st ed.

Place of Publication:

Amsterdam : Elsevier, 2008.

Language Note:

English

Summary:

The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising in the United States. Although estimates of the prevalence of these disorders vary, figures from the CDC indicate that 4% of all school age children are developmentally disabled. During infancy, many important milestones in behavioral development are shared between human and nonhuman primates. Learning more about the causes of abnormal development in monkeys has provided important insights into the mechanisms underlying neurodevelopmental disabi

Contents:

Front Cover; Primate Models of Children's Health and Developmental Disabilities; Copyright Page; Contents; Preface; Abbreviations; Chapter 1 Developmental Disabilities and Primate Models Defined; INTRODUCTION; DEVELOPMENTAL DISABILITY DEFINED?; PRIMATE MODELS DEFINED; NATURAL PRIMATE MODELS OF DEVELOPMENTAL DISABILITY; THE FUTURE OF PRIMATE MODELS; REFERENCES; Chapter 2 The Origin of Developmental Psychopathologies: Insights from Nonhuman Primate Studies; INTRODUCTION; SOCIAL COGNITION AND THE SOCIAL BRAIN; DEVELOPMENT OF SOCIAL SKILLS IN MACAQUES; DEVELOPMENT OF THE SOCIAL BRAIN IN MACAQUES

BEHAVIORAL OUTCOMES FOLLOWING SELECTIVE NEONATAL LESIONSIMPLICATION FOR DEVELOPMENTAL DISABILITIES IN HUMANS; CONCLUDING REMARKS AND FUTURE STUDIES; ACKNOWLEDGEMENTS; REFERENCES; Chapter 3 Macaque Models of Visual Development and Disability; NORMAL DEVELOPMENT OF VISION IN MACAQUE MONKEYS; VISUAL DISABILITY IN CHILDHOOD; EFFECTS OF VISUAL EXPERIENCE ON VISUAL DEVELOPMENT; NUTRITION AND VISUAL DEVELOPMENT; CONCLUSIONS; REFERENCES; Chapter 4 Spontaneous and Experimentally Induced Autoimmune Diseases in Nonhuman Primates; INTRODUCTION; IMMUNE MECHANISMS IN IMMUNE-MEDIATED INFLAMMATORY DISORDERS

SPONTANEOUS AUTOIMMUNITY AND AUTOIMMUNE DISORDERS IN NONHUMAN PRIMATESEXPERIMENTALLY INDUCED AUTOIMMUNE DISORDERS IN NONHUMAN PRIMATES; ARTHRITIS MODELS IN NONHUMAN PRIMATES; REFERENCES; Chapter 5 Self-injurious Behavior: Nonhuman Primate Models for the Human Condition; EXPRESSION OF SELF-INJURIOUS BEHAVIOR; DEVELOPMENT AND MAINTENANCE OF SELF-INJURIOUS BEHAVIOR; TREATMENT; CONCLUSIONS; REFERENCES; Chapter 6 Abnormal Behavior in Nonhuman Primates and Models of Development; INTRODUCTION; TYPES OF ABNORMAL BEHAVIOR IN MACAQUES; FACTORS CONTRIBUTING TO THE DEVELOPMENT OF ABNORMAL BEHAVIOR

THE FUNCTIONS OF ABNORMAL BEHAVIOR IN PRIMATES AND RELATIONSHIP TO MODELSREFERENCES; Chapter 7 Neurochemistry and Behavior: Nonhuman Primate Studies; INTRODUCTION; THE ROLE OF PARENTS IN CNS DEVELOPMENT; ATTACHMENT; AGGRESSION; BIOLOGICAL SUBSTRATES OF AGGRESSION; ETIOLOGICAL INVESTIGATIONS OF INDIVIDUAL DIFFERENCES; GENETIC CONTRIBUTIONS; GENE-ENVIRONMENT INTERACTION; CONCLUSIONS; REFERENCES; Chapter 8 Assessing Environmental Complexity for Both Normal and Deviant Development; INTRODUCTION; SENSATION; NOVELTY; COMPLEXITY; A THEORETICAL PROPOSAL; AN EXPERIMENTAL MODEL

RESPONSIVENESS TO THE ENVIRONMENTCONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 9 Prenatal Stress Influences on Neurobehavior, Stress Reactivity, and Dopaminergic Function in Rhesus Macaques; HUMAN STUDIES; POSSIBLE MECHANISMS OF PRENATAL STRESS EFFECTS; MATERNAL STRESS HORMONES; MORPHOLOGICAL AND NEUROTRANSMITTER CHANGES IN PRENATALLY-STRESSED ANIMALS; ADVANTAGES OF THE NONHUMAN PRIMATE MODEL OF PRENATAL STRESS EFFECTS; NONHUMAN PRIMATE PRENATAL STRESS STUDIES AT THE UNIVERSITY OF WASHINGTON, SEATTLE

PRENATAL STRESS EFFECTS IN RHESUS MONKEYS ON NEUROBEHAVIOR, HPA AXIS REGULATION, AND BRAIN FUNCTION AT THE UNIVERSITY OF WISCONSIN

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-281-07070-X

9786611070700

0-08-055406-7

OCLC:

476114671