Pathological pain : from molecular to clinical aspects.

Format:

Book

Conference/Event

Contributor:

Novartis Foundation (Japan) for the Promotion of Science.

Chadwick, Derek.

Goode, Jamie.

Conference Name:

Symposium on Pathological Pain: From Molecular to Clinical Aspects (2003 : Tsukuba-shi, Japan)

Series:

Novartis Foundation symposium ; 261.

Novartis Foundation symposium ; 261

Language:

English

Subjects (All):

Pain--Molecular aspects--Congresses.

Pain.

Pain--Pathophysiology--Congresses.

Physical Description:

1 online resource (ix, 271 pages) : illustrations

Edition:

1st ed.

Place of Publication:

Chichester, UK ; Hoboken, NJ, USA : John Wiley, 2004.

Language Note:

English

Summary:

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channels involved in nociception, the possible messages that cause neuropathic plasticity, spinal plasticity in neuropathy, plastic changes in opioid systems in neuropathy and opioid tolerance, and plastic changes related to pathological pain.

Contents:

PATHOLOGICAL PAIN: FROM MOLECULAR TO CLINICAL ASPECTS; Contents; Participants; Chair's introduction; Regulation mechanisms of vanilloid receptors; Discussion; Sodium channels and neuropathic pain; Discussion; Ion channel activities implicated in pathological pain; Discussion; General discussion I; Chronic pain and microglia: the role of ATP; Discussion; Neurotrophic influences on neuropathic pain; Discussion; Changes in DRG neurons and spinal excitability in neuropathy; Discussion; Functional reorganization of the spinal pain pathways in developmental and pathological conditions; Discussion

Central plasticity in pathological pain; Discussion; General discussion II; Anti-opioid systems in morphine tolerance and addiction - locus-specific involvement of nociceptin and the NMDA receptor; Discussion; Chronic morphine-induced plasticity among signalling molecules; Discussion; Opioid tolerance and neuroplasticity; Discussion; General discussion III; A mechanism-based understanding of bone cancer pain; Discussion; Mechanistic and clinical aspects of complex regional pain syndrome (CRPS); Discussion; Cortical pathophysiology of chronic pain; Discussion; Final discussion Translating basic research to the clinicIndex of contributors; Subject index

Notes:

"Symposium on Pathological pain: from molecular to clinical aspects, held at the Novartis Tsukuba Research Institute, Tsuskuba [sic], Japan, in collaboration with the Novartis Foundation (Japan) for the Promotion of Science, 30 September-2 October 2003; editors, Derek J. Chadwick (organizer) and Jamie Goode"--P. v.

Includes bibliographical references and indexes.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786610272327

9781280272325

1280272325

9780470869123

0470869127

9780470869116

0470869119

OCLC:

57598366