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Multiple sclerosis : a new paradigm / editor, Michel Geffard.
- Format:
- Book
- Series:
- Neurodegenerative Diseases - Laboratory and Clinical Research
- Neurodegenerative diseases--laboratory and clinical research series
- Language:
- English
- Subjects (All):
- Multiple sclerosis.
- Neurology.
- Physical Description:
- 1 online resource (209 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Hauppauge, N.Y. : Nova Science, c2011.
- Language Note:
- English
- Summary:
- Multiple Sclerosis (MS) is an inflammatory, auto-immune and degenerative disease of the central nervous system (CNS). Depending on the region affected, MS is a CNS disease of complex evolution, and is individual for each patient. However, clinically it has been recognised that in 85% of patients, the disease starts with a relapsing-remitting form. In a genetically predisposed patient, certain components of Gram-negative bacteria living in the mucous biotope would lie at the origin of immune system reactivation and the auto-immune components involved in the destruction of the actual tissues targeted. Thus, a new paradigm can be proposed; the Gram-negative bacteria that live in the intestinal epithelium and on other mucosal barriers, frequently rendered fragile by different external agents, would stimulate the immune system. This book presents and discusses research in the study of this new paradigm.
- Contents:
- A historic perspective on multiple sclerosis / Dolores González-Morón and Pablo Villoslada
- Bacterial role in the development of chronic multiple sclerosis / Alan Ebringer and Taha Rashid
- Animal models of multiple sclerosis / Beatriz Moreno and Pablo Villoslada
- Immunopathology and immuumunomodulation in experimental autoimmune encephalomyelitis and multiple sclerosis / R. Coveñas ... [et al.]
- Indirect visualization of specified antigenic modifications induced by nitric oxide in an experimental model of allergic encephalomyelitis / D. Bodet ... [et al.]
- A new paradigm for multiple sclerosis / Michel Geffard... [et al.].
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- Description based on print version record; title from PDF title page, viewed (07/23/2020).
- ISBN:
- 1-61209-006-0
- OCLC:
- 833143440
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