Acute lymphoblastic leukemia : etiology, pathogenesis and treatments / Severo Vecchione and Luigi Tedesco, editors.

Format:

Book

Contributor:

Vecchione, Severo.

Tedesco, Luigi.

Series:

Cancer etiology, diagnosis, and treatments.

Cancer etiology diagnosis and treatments

Language:

English

Subjects (All):

Lymphoblastic leukemia.

Physical Description:

1 online resource (251 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, Inc., c2012.

Language Note:

English

Summary:

Acute lymphoblastic leukemia (ALL) is a malignant disorder of the bone marrow in which a lymphoid precursor cell becomes genetically altered resulting in dysregulated proliferation and clonal expansion of neoplastic cells. It is the most common malignancy in children, representing nearly one third of all pediatric cancers. In this book, the authors present topical research in the study of acute lymphoblastic leukemia including genome wide association studies in pediatric acute lymphoblastic leukemia; mice deficient for the Slp65 signaling protein which is a model for ALL; histone deacetylase inhibitors and maintenance therapy in Ph negative adult acute lymphoblastic leukemia.

Contents:

Genome wide association studies in pediatric acute lymphoblastic leukemia : pathogenesis and therapy / Kyriaki Hatziagapiou ... [et al.]

Mice deficient for the Slp65 signaling protein : a model for Pre-B cell acute lymphoblastic leukemia / Van B.T. Ta, Rudi W. Hendriks

Childhood acute lymphoblastic leukemia / Adriana Zámecníkova

Systems approaches to childhood leukemogenesis / George I. Lambrou

Histone deacetylase inhibitors : pre-clinical and clinical evidence in treating acute lymphoblastic leukemia / Ana Lucia Abujamra

A therapeutic target in leukemia : the NK-1 receptor / Miguel Muñoz, Ana González-Ortega, Rafael Coveñas

Minimal residual disease monitoring in childhood acute lymphoblastic leukemia / Katerina Katsibardi

Clinical relevance and application of cytogenetic approaches in pediatric acute lymphoblastic leukaemia / Maria Braoudaki

Maintenance therapy in Ph negative adult acute lymphoblastic leukemia / Michael Doubek, Jirí Mayer

The role of innate and adaptive immunity in childhood acute lymphoblastic leukemia / Maria Hatzistilianou, Agiou Ioannou.

Notes:

"Nova biomedical."

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61470-905-X

OCLC:

828868938