Outstanding marine molecules / edited by Stephane La Barre and Jean-Michel Kornprobst.

Format:

Book

Author/Creator:

La Barre, Stéphane, author.

Language:

English

Subjects (All):

Natural products.

Physical Description:

1 online resource (535 p.)

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-VCH Verlag, 2014.

Language Note:

English

Summary:

Using a number of outstanding examples, this text introduces readers to the immense variety of marine natural compounds, the methodologies to characterize them and the approaches to explore their industrial potential. Care is also taken to discuss the function and ecological context of the compounds. Carefully produced and easy to read, this book serves students and professionals wishing to familiarize themselves with the field, and is ideally suited as a course book for both industry to academia.

Contents:

Outstanding Marine Molecules: Chemistry, Biology, Analysis; Contents; List of Contributors; Foreword; Preface; Part One: Outstanding Marine Molecules from a Chemical Point of View; 1 Marine Cyanotoxins Potentially Harmful to Human Health; 1.1 Introduction; 1.2 Marine Cyanobacteria as Causative Agent of Ciguatera-Like Poisoning; 1.2.1 Ciguatera Fish Poisoning; 1.2.2 Ciguatera Shellfish Poisoning (CSP): A New Ecotoxicological Phenomenon; 1.2.3 Ciguatera-Like Poisonings Involve Complex Mixtures of Cyanotoxins; 1.2.3.1 Ciguatoxins and Homoanatoxin; 1.2.3.2 Ciguatoxins and Saxitoxins

1.2.3.3 Ciguatoxins and Palytoxins1.3 Marine Cyanobacteria: A Potential Risk for Swimmers; 1.4 Microcystins Could also be Found in the Sea; 1.5 Risk of Neurodegenerative Disease in the Sea; 1.6 Conclusion and Future Prospects; Acknowledgments; References; 2 Outstanding Marine Biotoxins: STX, TTX, and CTX; 2.1 Introduction; 2.2 Saxitoxins (STXs) in Paralytic Shellfish Poisoning; 2.2.1 Causes of Paralytic Shellfish Poisoning; 2.2.2 Saxitoxins (STXs); 2.2.2.1 Chemical Aspects of the STXs; 2.2.2.2 Detection of PSP Toxins; 2.2.2.3 Poisoning Records

2.3 Tetrodotoxin (TTX) in Puffer Fish Poisoning (PFP)2.3.1 Puffer Fish Poisoning (PFP); 2.3.1.1 Chemical Aspects of TTX; 2.3.1.2 Detection of TTXs; 2.4 Ciguatoxin (CTX) in Ciguatera Fish Poisoning (CFP); 2.4.1 Ciguatera Fish Poisoning (CFP); 2.4.2 Ciguatoxins; 2.4.2.1 Chemical Aspects; 2.4.2.2 Detection of CTX Toxins; 2.4.2.3 Poisoning Records; 2.4.2.4 Persistence and Recurrence of Symptoms; 2.4.2.5 Fish Containing Ciguatoxins; 2.4.2.6 Qualitative and Quantitative Methods for Toxins Detection; 2.5 Conclusions; References

3 Impact of Marine-Derived Penicillium Species in the Discovery of New Potential Antitumor Drugs 3.1 Introduction; 3.2 Molecules Isolated from Marine-Derived Penicillium Species With Potent Cytotoxic Activity; 3.3 Marine-Derived Cytotoxic Penicillium; 3.3.1 Where Were Marine-Derived Penicillium Searched and Isolated?; 3.3.2 Which Penicillium Species?; 3.4 What are these Promising Molecules from Marine Penicillium?; 3.4.1 Statistics; 3.4.2 Focus on Interesting Molecules; 3.4.2.1 Cytotoxic Alkaloids: The Example of Communesins

3.4.3 Cytotoxic Alkaloids/Diketopiperazine Compounds: Examples of Fructigenine A and Verticillin Derivatives 3.4.3.1 Fructigenine A (= Rugulosovin B = Puberulin); 3.4.3.2 Verticillin A and Derivatives; 3.4.4 Cytotoxic Sesquiterpenes: Ligerin, a Chlorinated Sesquiterpene; 3.4.4.1 Ligerin is Produced by a New Species of Penicillium; 3.4.4.2 Isolation of Ligerin; 3.4.4.3 The Chlorine Atom: The Originality of Ligerin's Chemical Structure; 3.4.4.4 The Many Structural Analogs of Ligerin; 3.4.4.5 Ligerin Semisynthesis; 3.4.4.6 Bioactivities; 3.5 Conclusions; References

4 Astonishing Fungal Diversity in Deep-Sea Hydrothermal Ecosystems: An Untapped Resource of Biotechnological Potential?

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed April 2, 2014).

ISBN:

9783527681532

3527681531

9783527681501

3527681507

9783527681525

3527681523

OCLC:

874322280