Clinical laboratory animal medicine : an introduction / Karen Hrapkiewicz, Lesley Colby, Patricia Denison.

Format:

Book

Author/Creator:

Hrapkiewicz, Karen.

Contributor:

Colby, Lesley.

Denison, Patricia.

Language:

English

Subjects (All):

Animals--Diseases.

Animals.

Laboratory animals.

Physical Description:

1 online resource (449 p.)

Edition:

Fourth edition.

Place of Publication:

Ames, Iowa : Wiley, 2013.

Language Note:

English

Summary:

Clinical Laboratory Animal Medicine: An Introduction, Fourth Edition offers a user-friendly guide to the unique anatomy and physiology, care, common diseases, and treatment of small mammals and nonhuman primates. Carefully designed for ease of use, the book includes tip boxes, images, and review questions to aid in comprehension and learning. The Fourth Edition adds new information on transgenic mice, drug dosages, techniques, and environmental enrichment, making the book a comprehensive working manual for the care and maintenance of common laboratory animals. The book includes

Contents:

Cover; Title page; Copyright page; Dedication; Note; Contents; About the Authors; Preface; About the Companion Web Site; 1: Introduction to Laboratory Animal Medicine; Animals Used in Research, Product Safety Testing, and Education; Biomedical Research; Product Safety Testing; Education; Animal Usage Statistics; Funding Sources; Regulatory Oversight and Accreditation; Institutional Animal Care and Use Committee; Ethical Considerations; The 3Rs: Replacement, Refinement, and Reduction; Animal Rights and Animal Welfare; Random Source versus Purpose Bred Animals; Nonhuman Primate Use

OrganizationsAmerican Association for Laboratory Animal Science; American Society of Laboratory Animal Practitioners; American College of Laboratory Animal Medicine; National Association for Biomedical Research; Foundation for Biomedical Research; Institute for Laboratory Animal Research; References; Further Reading; 2: Regulations, Policies, and Principles Governing the Care and Use of Laboratory Animals; Animal Welfare Act and Regulations; The Chimpanzee Health Improvement, Maintenance, and Protection Act; Office of Laboratory Animal Welfare and Public Health Service Policy

Good Laboratory Practice RegulationsGuide for the Care and Use of Laboratory Animals; Guide for the Care and Use of Agricultural Animals in Research and Teaching; Occupational Health and Safety; Association for Assessment and Accreditation of Laboratory Animal Care International; Animal Welfare Information Center; State Regulations; References; Further Reading; 3: Facility Design, Equipment, Housing, and Management; Laboratory Animal Facility Design; Biosecurity; Conventional Facilities; Barrier Facilities; Containment or Biohazard Facilities; Facility Equipment; Cage Washers

Watering EquipmentFood and Bedding Materials; Housing; Rodent Housing; Housing for Other Small Mammals; Specialized Housing Systems; Management; Laboratory Animal Allergies; References; Further Reading; 4: Mice; Genetics; Microbiologic Classifications; Uses; Behavior; Anatomic and Physiologic Features; Breeding and Reproduction; Husbandry; Housing and Environment; Environmental Enrichment and Social Housing; Feeding and Watering; Sanitation; Techniques; Handling and Restraint; Identification; Blood Collection; Urine Collection; Drug Administration; Anesthesia, Surgery, and Postoperative Care

Imaging TechniquesEuthanasia; Humane Endpoints; Special Techniques: Transgenic Production Technology; Pronuclear Injection; Gene Targeting; Genotyping; Therapeutic Agents; Introduction to Diseases of Mice; Bacterial Diseases; Viral Diseases; Parasitic Diseases; Neoplasms; Miscellaneous Conditions; References; Further Reading; 5: Rats; Genetics; Microbiologic Classifications; Uses; Behavior; Anatomic and Physiologic Features; Breeding and Reproduction; Husbandry; Housing and Environment; Environmental Enrichment and Social Housing; Feeding and Watering; Sanitation; Techniques

Handling and Restraint

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed December 9, 2013).

ISBN:

1-118-68596-2

1-118-68594-6

OCLC:

861081376