Information processing by biochemical systems : neural network-type configurations / Orna Filo, Noah Lotan.

Format:

Book

Author/Creator:

Filo, Orna.

Contributor:

Lotan, Noah.

Language:

English

Subjects (All):

Biocomputers.

Neural networks (Computer science).

Information technology.

Physical Description:

1 online resource (168 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, NJ : John Wiley & Sons, c2010.

Language Note:

English

Summary:

A Research-Driven Resource on Building Biochemical Systems to Perform Information Processing Functions Information Processing by Biochemical Systems describes fully delineated biochemical systems, organized as neural network-type assemblies. It explains the relationship between these two apparently unrelated fields, revealing how biochemical systems have the advantage of using the ""language"" of the physiological processes and, therefore, can be organized into the neural network-type assemblies, much in the way that natural biosystems are. A wealth of information is included c

Contents:

INFORMATION PROCESSING BY BIOCHEMICAL SYSTEMS; CONTENTS; Preface; Terminology; List of Symbols and Acronyms; 1 Introduction and Literature Survey; 1.1 Introduction; 1.2 Computational Processes Based on Biological Principles; 1.2.1 Modeling Biological Processes; 1.2.2 Artificial Neural Networks; 1.3 Molecular and Biomolecular Electronics; 1.3.1 Motivation; 1.3.2 Molecular Electronics; 1.3.3 Biomolecular Electronics; 1.4 Biochemical Devices Based on Enzymic Reactions; 1.5 Oscillations in Biochemical Systems; 1.6 Kinetic Characteristics of Cyclic Enzyme Systems

2 Background and Goals of This Study3 Materials and Methods; 3.1 Materials; 3.2 Instruments; 3.3 Experimental Methods; 3.3.1 Determination of Kinetic Constants; 3.3.2 Determination of the Inhibition Constant for Inhibition of Glutathione Reductase by Glucose-6-Phosphate; 3.3.3 Immobilization on Affi-Gel 10; 3.3.4 Assay for Glucose-6-Phosphate Dehydrogenase; 3.3.5 Assay for Glutathione Reductase; 3.4 Computational Methods; 4 Results; 4.1 The Basic System: Theoretical Considerations and Results; 4.1.1 Characteristics of the Basic System; 4.1.2 The Basic System as an Information-Processing Unit

4.1.3 Analytical Models for the Basic System4.1.4 Results of Numerical Simulations for the Basic System; 4.2 Neural Network-Type Biochemical Systems for Information Processing; 4.2.1 Network A; 4.2.2 Network B; 4.2.3 Network C; 4.3 The Basic System: Experimental Results; 4.3.1 Deciding on the Experimental System; 4.3.2 Kinetic Study of the Experimental System; 4.3.3 Control of the Input Signal; 4.3.4 The Basic System in a Fed-Batch Reactor; 4.3.5 Internal Inhibition in the Basic System; 4.3.6 Prediction of the Analytical Model Considering Internal Inhibition in a Fed-Batch Reactor

4.3.7 Immobilization of G6PDH and GR4.3.8 The Basic System in a Packed Bed Reactor; 4.4 The Extended Basic System: Theoretical Considerations and Results; 4.4.1 Characteristics of the Extended Basic System; 4.4.2 The Extended Basic System as an Information-Processing Unit; 4.4.3 Analytical Model for the Extended Basic System; 4.4.4 Results of Numerical Simulations for the Extended Basic System; 5 Discussion; 5.1 The Basic System; 5.1.1 Fed-Batch Reactor: Numerical Simulations; 5.1.2 Continuous Reactor: Numerical Simulations; 5.1.3 Assessment of Experimental Results

5.2 The Extended Basic System5.3 Biochemical Networks; 5.4 Comparing Artificial Neural Networks with Biochemical Networks; 5.5 Comparing Biochemical Networks to Computational Models; 6 Conclusions; References; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786612686641

9781282686649

128268664X

9780470552681

0470552689

9780470552674

0470552670

OCLC:

536336745