Essential evidence : medicine that matters / David Slawson ... [et al.].

Format:

Book

Contributor:

Slawson, David C.

Language:

English

Subjects (All):

Evidence-based medicine.

Clinical medicine.

Physical Description:

1 online resource (542 p.)

Edition:

11th ed.

Place of Publication:

Hoboken, N.J. : Wiley-Interscience, c2007.

Language Note:

English

Summary:

This manual helps clinicians easily to find the best available evidence to facilitate sound medical decisions. It is the first published compilation of highly relevant InfoPOEMs that the editors believe has the potential to change a clinician's practice. The editors have selected over 300 of the most influential, compelling POEMs, and organized them by topic for easy reference. Each POEM contains:Clinical Question: Poses a question that the study seeks to answer.Bottom line: Summarizes the findings of the research and places these findings into the context with the known informat

Contents:

Essential Evidence: Medicine that Matters; Contents; Preface; Taking an Evidence-Based Approach to the Care of Patients; How to Become an Information Master: Feeling Good about NOT Knowing Everything; InfoPOEMs (Patient-Oriented Evidence that Matters); Cancer; Breast cancer; Most women with breast cancer have no risk factors; Raloxifene reduces breast cancer risk (CORE); Raloxifene and tamoxifen equally effective in reducing breast cancer risk; Raloxifene decreases breast cancer risk, no effect on cardiovascular diseaserisk (RUTH); MRI more accurate than mammogram in high-risk patients

MRI more sensitive than mammography in high-risk women (MARIBS)Digital mammography more sensitive for younger women; Mammography results in overdiagnosis; Annual mammography starting at 40 doesn't lower breast cancer mortality; Gynecologic cancers; Many unnecessary Pap smears are performed after hysterectomy; Specific HPV strains are associated with cervical cancer risk; Vaccine effective against HPV; Bivalent vaccine against HPV effective for 4.5 years; Liquid-based not better than conventional Pap; Endometrial sampling adequate for diagnosing endometrial cancer; Melanoma

Melanoma incidence really not risingLifetime risk of mole transforming to melanoma very low; 0.7% of congenital melanocytic nevi become malignant; Dermoscopy with validated criteria more sensitive than unaided eye; Larger margins better in melanoma >2mm thick; Prevention and screening; Antioxidants don't prevent GI cancers, and may increase overall mortality; Vitamin E doesn't lower women's risk of cardiovascular disease or cancer; Antioxidants don't prevent colorectal cancer; Mammography, FOBT and CXR don't reduce all-cause mortality

Spiral CT detects early lung cancer, but screening use is prematureCancer linked to some diabetes treatments; Prostate cancer; Finasteride of mixed benefit in preventing prostate cancer; Prostate cancer screening every 4 years as good as annually; False-positive PSA associated with increased worry, fears; Elevated PSA should be confirmed before biopsy; Radical prostatectomy improves outcomes in symptom-detected prostate cancer; Cardiology; Acute myocardial infarction and acute coronary syndromes; Early metoprolol in acute MI: no benefit, possible harm (COMMIT; CCS-2)

Insulin/dextrose infusion ineffective in AMI (HI-5)Early initiation of statins following ACS does not improve outcomes; Antibiotics not effective in acute coronary syndromes; ABCDE approach to non-ST-segment elevation ACS; Door-to-balloon time important in STEMI; Routine invasive strategy may be preferred for ACS; Intensive medical tx + selective PCI preferred for non-ST ACS; Invasive tx slightly better in non-ST-elevation ACS (RITA3); In ACS, 5years of invasive tx decreases MI but not all cause mortality (FRISC-II); Captopril = losartan for reducing all-cause mortality after Ml

Captopril better than valsartan or combination post-MI

Notes:

Includes index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

0-470-59768-2

1-282-31700-8

9786612317002

0-470-48481-0

OCLC:

463436644