Parasitic flatworms : molecular biology, biochemistry, immunology and physiology / edited by Aaron G. Maule and Nikki J. Marks.

Format:

Book

Contributor:

Maule, Aaron G.

Marks, Nikki J.

Language:

English

Subjects (All):

Platyhelminthes.

Physical Description:

1 online resource (468 p.)

Edition:

1st ed.

Place of Publication:

Wallingford, UK ; Cambridge, MA : CABI, c2006.

Language Note:

English

Summary:

This book examines recent research into the molecular biology, genomics and transcriptomics of, and novel control strategies for, flatworm parasites. These include Cestodes (tapeworms) and Trematodes (flukes, schistosomes etc), which are the cause of a number of diseases of medical and veterinary importance. The book explores three main areas: phylogeny, genetics and transcriptomes; immunobiology, host-parasite interaction and control; and protein function, metabolism and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-li

Contents:

The evolution of parasitism in flatworms / D.T.J. Littlewood

Genomes and genomics of parasitic flatworms / D.A. Johnston

Genetic discrimination of echinococcus species and strains / D.P. McManus

Ribosomal DNA variation in parasitic flatworms / D. Blair

Genetic studies on monogeneans with emphasis on Gyrodactylus / C.O. Cunningham and I. Matejusova

The schistosome transcriptome / S. Verjovski-Almeida and R. DeMarco

Transgenic flatworms / C.G. Grevelding

Immunobiology of schistosomes / S.G. Forrester and E.J. Pearce

Cestode infection : immunological considerations from host and tapeworm perspectives / D.M. McKay and R.A. Webb

Signal transduction at the host-parasite interface / T.P. Yoshino, J.J. Vermeire and J.E. Humphries

Parasite effects on the snail host transcriptome / M. Knight and N. Raghavan

Developments in the chemotherapy of parasitic flatworms / G.C. Coles

Drug resistance in schistosomes / T.A. Day and S. Botros

Praziquantel : mechanism of action / R.M. Greenberg

Cestode vaccine development / M.W. Lightowlers

The development of a schistosome vaccine / R.A. Wilson and P.S. Coulson

Flatworm parasite proteomics / R.M. Morphew, J. Barrett and P.M. Brophy

Proteases in trematode biology / J.P. Dalton, C.R. Caffrey, M. Sajid, C. Stack, S. Donnelly, A. Loukas, T. Don, J. McKerrow, D.W. Halton and P.J. Brindley

Signalling molecules and nerve-muscle function / A.G. Maule, N.J. Marks and T.A. Day

Unusual aspects of metabolism in flatworm parasites / A.G.M. Tielens and J.J. van Hellemond

Glycoconjugate structures / M. Wuhrer and R. Geyer

Gene silencing in flatworms using RNA interference / P.J. Skelly.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-280-73550-3

9786610735501

1-84593-039-8

OCLC:

133159509