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System modeling in cell biology : from concepts to nuts and bolts / edited by Zoltan Szallasi, Jorg Stelling, Vipul Periwal.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Cytology--Data processing.
- Cytology.
- Cytology--Mathematical models.
- Cytology--Computer simulation.
- Biological systems.
- Physical Description:
- 1 online resource (465 p.)
- Edition:
- 1st ed.
- Other Title:
- System modeling in cellular biology
- Place of Publication:
- Cambridge, Mass. : MIT Press, c2006.
- Language Note:
- English
- Summary:
- This is an introduction and overview of system modelling in biology that is accessible to researchers from different fields including biology, computer science, mathematics, statistics physics, and biochemistry.
- Contents:
- Contents; Preface; I GENERAL CONCEPTS; 1 The Role of Modeling in Systems Biology; 2 Complexity and Robustness of Cellular Systems; 3 On Modules and Modularity; II MODELING APPROACHES; 4 Bayesian Inference of Biological Systems: The Logic of Biology; 5 Stoichiometric and Constraint-based Modeling; 6 Modeling Molecular Interaction Networks with Nonlinear Ordinary Differential Equations; 7 Qualitative Approaches to the Analysis of Genetic Regulatory Networks; 8 Stochastic Modeling of Intracellular Kinetics; 9 Kinetics in Spatially Extended Systems; III MODELS AND REALITY
- 10 Biological Data Acquisition for System Level Modeling-An Exercise in the Art of Compromise11 Methods to Identify Cellular Architecture and Dynamics from Experimental Data; 12 Using Control Theory to Study Biology*; 13 Synthetic Gene Regulatory Systems; 14 Multilevel Modeling in Systems Biology: From Cells to Whole Organs; IV COMPUTATIONAL MODELING; 15 Computational Constraints on Modeling in Systems Biology; 16 Numerical Simulation for Biochemical Kinetics; 17 Software Infrastructure for Effective Communication and Reuse of Computational Models; A Software Tools for Biological Modeling
- ReferencesContributors; Index
- Notes:
- OCLC-licensed vendor bibliographic record.
- "A Bradford book."
- Includes bibliographical references (p. [385]-433) and index.
- ISBN:
- 0-262-25706-8
- 1-282-09679-6
- 9786612096792
- 1-4237-7254-7
- OCLC:
- 68816342
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