Protein crystallography : a concise guide / Eaton E. Lattman and Patrick J. Loll.

Format:

Book

Author/Creator:

Lattman, Eaton E. (Eaton Edward), 1940-

Contributor:

Loll, Patrick J. (Patrick John), 1958-

Language:

English

Subjects (All):

Proteins--Structure.

Proteins.

X-ray crystallography.

Physical Description:

1 online resource (152 p.)

Edition:

1st ed.

Place of Publication:

Baltimore : Johns Hopkins University Press, 2008.

Language Note:

English

Summary:

The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

Contents:

""Contents""; ""Preface""; ""Chapter 1. Introduction""; ""1.1 What Is X-ray Crystallography?""; ""1.2 A Quick Look at Protein Crystals""; ""1.3 Noncrystalline Specimens""; ""1.4 Summary""; ""Further Reading""; ""Chapter 2. A Physical Understanding of Diffraction""; ""2.1 What Is Diffraction?""; ""2.2 Diffraction from One-Dimensional Crystals""; ""2.3 Reconstructing Images from Diffraction Patterns""; ""2.4 Summary""; ""Further Reading""; ""Chapter 3. Diffraction from Three-Dimensional Crystals""; ""3.1 The Electron Density Function in Three Dimensions""

""3.2 Calculating the Diffraction Pattern from a Known Structure""""3.3 Summary""; ""Further Reading""; ""Chapter 4. Phase Determination by Isomorphous Replacement""; ""4.1 Measuring the Phases""; ""4.2 MAD Phasing""; ""4.3 Fitting Models to Experimental Electron Density Maps""; ""4.4 Summary""; ""Further Reading""; ""Chapter 5. The Patterson Function""; ""5.1 Definition of the Patterson Function""; ""5.2 Using the Patterson Function to Locate Atoms""; ""5.3 Summary""; ""Further Reading""; ""Chapter 6. Phasing with Partially Known Structures""; ""6.1 Difference Fourier Maps""

""6.2 Molecular Replacement""""6.3 Summary""; ""Further Reading""; ""Chapter 7. Crystallographic Refinement""; ""7.1 Refinement Improves the Model""; ""7.2 Least-Squares Refinement""; ""7.3 Summary""; ""Further Reading""; ""Glossary""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""H""; ""I""; ""L""; ""M""; ""N""; ""O""; ""P""; ""R""; ""S""; ""T""; ""U""; ""V""; ""W""; ""Index""; ""A""; ""B""; ""C""; ""D""; ""E""; ""F""; ""G""; ""H""; ""I""; ""K""; ""L""; ""M""; ""N""; ""O""; ""P""; ""Q""; ""R""; ""S""; ""T""; ""U""; ""V""; ""W""; ""X""; ""Z""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

0-8018-9684-3

0-8018-8808-5

OCLC:

923195244