Essentials of cardiovascular physiology / Harvey V. Sparks, Jr. and Thom W. Rooke ; original illustrations by Robert R. Lorenz.

Format:

Book

Author/Creator:

Sparks, Harvey V., 1938-

Contributor:

Rooke, Thom W.

Language:

English

Subjects (All):

Cardiovascular system--Physiology.

Cardiovascular system.

Blood--Circulation.

Blood.

Physical Description:

1 online resource (224 p.)

Edition:

1st ed.

Place of Publication:

Minneapolis : University of Minnesota Press, c1987.

Language Note:

English

Summary:

Essentials of Cardiovascular Physiology was first published in 1987.Modern cardiovascular physiology ranges from subcellular function to integrated responses that involve all of the body's systems, yet medical students are usually given only a few weeks in which t master this diverse and complex subject. To help overcome these difficulties, Harvey Sparks, Jr., M.D., and Thom W. Rooke, M.D., have written an introductory text which can be read and understood in the two-to-three week period most curricula provide for cardiovascular physiology.Each of the eight chapters integrates basic science with areas of clinical relevance in the simplest, most succinct way for students of medicine, physiology, nursing, and pharmacology. The authors' aim throughout is to select those facts and concepts that are essential to a solid initial comprehension of the subject. The numerous illustrations and flow diagrams will help students understand the complex interrelationships among factors regulating the heart and blood vessels -- and will also be useful for rapid review, because they cover most of the text's major points. Each chapter includes references leading the student to expand treatments of individual topics, and from there to the original literature. The topics covered include: overall arrangement of the circulatory system, electrical activity of the heart, the heart as a pump, systematic circulation, neural and hormonal control of circulation, regulation of flow and exchange, regulation of blood flow in specific organs, and integrated cardiovascular responses.

Contents:

Intro

Contents

Preface

Acknowledgments

Chapter 1 Once Around the Circulation

Systemic and Pulmonary Circulation

Transport

Blood

Hemostasis

Suggested Readings

Chapter 2 Electrical Activity of the Heart

Ionic Basis for Electrical Activity

Membrane Potential of Cardiac Cells

Molecular Basis of Cation Movements Across Cardiac Cell Membranes

Refractory Period

Ionic Basis for the Cardiac Membrane Potential

Membrane Changes in Ventricular Cells

Membrane Changes in Nodal Cells

Propagation of Electrical Activity

Conduction of the Action Potential

The Electrocardiogram

Interpretation of the Electrocardiogram

Change in Mass

Abnormal Dipoles

Chapter 3 The Heart as a Pump

Molecular Basis of Cardiac Muscle Contraction

Excitation-Contraction Coupling

The Contraction of Isolated Cardiac Muscle

Length-Tension Relationship

Preload and Afterload

Force-Velocity Relationship

Contractility

The Cardiac Cycle

Cardiac Output

Factors Influencing Cardiac Output

Summary of Determinants of Cardiac Output

Measurement of Cardiac Output

Energetics of Cardiac Function

Chapter 4 Systemic Circulation

Pressure-Flow Relationship

Mean Arterial Pressure

PuIse Pressure

Normal Range of Arterial Pressure

Determinants of Blood Pressure

Measurement of Arterial Pressure

Total Peripheral Resistance

Blood Volume

Chapter 5 Neural and Hormonal Control of the Circulation

Autonomic Control

Functional Anatomy

Neurotransmitters

Norepinephrine

Adrenergic Receptors

Alpha-adrenergic Receptors

Beta-adrenergic Receptors

Acetylcholine

CNS Areas Involved in Control of the Cardiovascular System

Spinal

Medullary

Cortical

Neurotransmitters in the CNS.

Reflex Behavior of the Cardiovascular System

Baroreceptor Reflex

Volume Receptor Reflex

Chemoreceptor Reflex

Other Reflexes

Corticohypothalamic Cardiovascular Patterns

Hormonal Control System

Adrenal Medulla

Vasopressin

Renin-Angiotensin-Aldosterone System

Erythropoietin

Atrial Natriuretic Peptide

Chapter 6 Regulation of Flow and Exchange

Endothelial Cells

Vascular Smooth Muscle

Exchange Across the Capillary Wall

Diffusional Exchange

Capillary Filtration and Reabsorption

The Lymphatic System

Edema

Chapter 7 Regulation of Blood Flow

The Pulmonary Circulation

Skeletal Muscle Blood Flow

Cutaneous Blood Flow

Cerebral Blood Flow

Splanchnic Blood Flow

Renal Blood Flow

Coronary Blood Flow

Chapter 8 Integrated Cardiovascular Responses

Cardiac Output, Venous Return, and Central Blood Volume

The Cardiovascular Response to Standing

Reflexes

Muscle and Respiratory Pumps

Constriction of Arterioles

Long-Term Adjustments

Exercise

Index

A

B

C

D

E

F

G

H

I

J

K

L

M

N

O

P

Q

R

S

T

V

W.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographies and index.

ISBN:

9780816655755

0816655758

9780816614738

0816614733

OCLC:

230204842