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Iodotrifluoromethane toxicity review / Subcommittee on Iodotrifluoromethane, Committee on Toxicology, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council.

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Format:
Book
Contributor:
National Research Council (U.S.). Subcommittee on Iodotrifluoromethane.
Language:
English
Subjects (All):
Fluorohydrocarbons--Toxicology.
Fluorohydrocarbons.
Iodides--Toxicology.
Iodides.
Fire extinguishing agents.
Trifluoroiodomethane--Toxicology.
Trifluoroiodomethane.
Physical Description:
1 online resource (96 p.)
Edition:
1st ed.
Place of Publication:
Washington, D.C. : National Academies Press, c2004.
Language Note:
English
Summary:
The U.S. military is considering using a compound called iodotrifluoromethane (CF3I) for fire suppression to replace previously-used compounds (halons) that are being phased out because they deplete the ozone layer. This report reviews available toxicological data on CF3I and evaluates the scientific basis of the U.S. Army's proposed exposure limit of 2,000 parts per million (ppm). The report recommends that CF3I be used for fire suppression in normally unoccupied spaces because of its potential to cause cardiac sensitization in test animals. The report also recommends that further genotoxicity testing be conducted (testing for changes in genetic material), and that CF3I be assessed for its potential to cause cancer. Should the Army decide to use CF3I, information should be collected and evaluated on how much of the chemical or any of its degradation products might be released and how often.
Contents:
""Front Matter""; ""Preface""; ""Abbreviations""; ""Contents""; ""Summary""; ""1 Introduction""; ""2 Physical and Chemical Properties And Efficacy""; ""3 Health Effects: Toxicity Studies""; ""4 Cardiac Sensitization""; ""5 Physiologically Based Pharmacokinetic Modeling""; ""References""; ""Appendix A Biographical Information on Subcommittee on Iodotrifluoromethane""; ""Appendix B Toxicity Review for Iodotrifluoromethane (CF3I): 2002 Update""
Notes:
Description based upon print version of record.
Includes bibliographical references.
ISBN:
9786610175857
9780309182270
0309182271
9781280175855
1280175850
9780309545501
0309545501
OCLC:
923272741

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