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Hepatitis C viruses : genomes and molecular biology
- Format:
- Book
- Author/Creator:
- Tan, Seng-Lai, author.
- Language:
- English
- Subjects (All):
- Hepatitis C virus.
- Hepacivirus--genetics.
- Genomics.
- Molecular Biology.
- Medical Subjects:
- Hepacivirus--genetics.
- Genomics.
- Molecular Biology.
- Physical Description:
- 1 online resource (ix, 469 pages) : illustrations (some color)
- Other Title:
- Hepatitis C Viruses
- Place of Publication:
- [Place of publication not identified] Horizon Bioscience 2006
- Language Note:
- English
- Summary:
- This is an essential book for anyone studying HCV. Internationally renowned authors review and discuss the most recent aspects of HCV infection, replication and molecular biology.
- Contents:
- HCV genome and life cycle
- HCV 5' and 3'UTR: when translation meets replication
- Assemble and interact: pleiotropic functions of the HCV core protein
- HCV glycoproteins: assembly of a functional E1-E2 heterodimer HCV NS2/3 protease
- HCV NS3-4A serine protease
- HCV helicase: structure, function, and inhibition
- HCV NS4B: from obscurity to central stage
- HCV NS5A: a multifunctional regulator of cellular pathways and virus replication
- Biochemical activities of the HCV NS5B RNA-dependent RNA polymerase
- HCV replicon systems
- Animal models for HCV study
- HCV regulation of host defense
- Regulation of adaptive immunity by HCV
- Recombinant vesicular stomatitis virus (VSV) and other strategies in HCV vaccine designs and immunotherapy
- Development of an infectious HCV cell culture system.
- Notes:
- Bibliographic Level Mode of Issuance: Monograph
- ISBN:
- 9781904933205
- 1904933203
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