Endocrinology : an integrated approach / S.S. Nussey and S.A. Whitehead.

Format:

Book

Author/Creator:

Nussey, Stephen, author.

Contributor:

Whitehead, Saffron A.

Language:

English

Subjects (All):

Endocrinology.

Internal medicine.

Physical Description:

1 online resource (371 p.)

Place of Publication:

Oxford [England] : BIOS Scientific Publishers Ltd., 2002.

Language Note:

English

Summary:

Traditionally, endocrinology textbooks have been either short notes or multi-author, multi-volume monster, all of which present clinical material last and often only briefly. Endocrinology is different and used real cases to lead readers into the text and then describes the biochemistry, physiology, and anatomy they need to understand the case. The user-friendly design utilizes colour-coded boxes to highlight the basic scientific and clinical material required and also to describe the latest more advanced evidence. Typical clinical cases are included, along with more idiosyncratic cases to capture attention and highlight the cross-disciplinary nature of medicine. Endocrinology is the first book to address the requirement for integrated basic science and clinical practice, to encourage problem-based learning, and to lead readers deep into the subject. Unique benefits: * integrates basics sciences and clinical practice * features more real clinical cases than any similar book to emphasize problem-based learning * comprehensive and yet approachable * includes a comprehensive range of questions and answers to test understanding

Contents:

""Front Cover""; ""Endocrinology: An Integrated Approach""; ""Copyright Page""; ""Contents ""; ""Preface""; ""1. Principles of endocrinology""; ""Functions of hormones and their regulation""; ""Chemical signalling � endocrine, paracrine, autocrine and intracrine mechanisms""; ""Chemical classification of hormones and their synthesis""; ""Hormone synthesis""; ""Transport of hormones in the circulation and their half-lives""; ""Hormone receptors � cell surface""; ""Hormone receptors � intracellular""; ""Hormones and gene transcription""; ""Hormone receptor regulation""

""Neuroendocrine interactions""""Hormones and the immune system""; ""Hormones, growth promotion and malignancy""; ""Genes, mutations and endocrine function""; ""Clinical evaluation of endocrine disorders""; ""2. The endocrine pancreas""; ""Glucose turnover""; ""Anabolic and catabolic phases of glucose metabolism""; ""Actions of insulin and glucagon""; ""Lipid metabolism � insulinopenia and diabetic ketosis""; ""Protein metabolism and the anabolic actions of insulin""; ""Definition and diagnosis of diabetes mellitus""; ""Etiology of type I DM""; ""Prevention of type I DM""

""Structure, synthesis and metabolism of insulin and glucagon""""Anatomical features of pancreatic islets in relation to hormone secretion and its control""; ""Control of insulin and glucagon secretion""; ""Type 2 DM""; ""Causes of DM""; ""Genetic disorders of β-cell function""; ""Counter-regulatory hormones and DM""; ""Complications of DM""; ""Macrovascular circulatory changes""; ""Microvascular changes � diabetic retinopathy, nephropathy and neuropathy""; ""Diabetes and the neuropathic foot""; ""Diabetes and insulin resistance of pregnancy""

""Development of the pancreas: effects of DM on organogenesis""""Treatment of DM � rationale and practical considerations""; ""Hypoglycemia""; ""Physiological responses to hypoglycemia and its treatment""; ""Hypoglycemia and insulinoma""; ""Hypoglycemia in infancy""; ""Disorders of the α, γ and PP cells of the islets""; ""Clinical case questions""; ""3. The thyroid gland""; ""Iodine intake""; ""Anatomical features of the thyroid gland""; ""Iodine trapping and thyroid function""; ""Synthesis of thyroid hormones""; ""Actions of thyroid hormones""

""Control of thyroid hormone synthesis and secretion""""Hyperthyroidism � Graves' disease""; ""Surgical anatomy and embryology of the thyroid gland""; ""Primary hypothyroidism � Hashimoto's disease and myxedema""; ""Secondary hypothyroidism""; ""Hypothyroidism in infancy and childhood""; ""Thyroid hormone resistance""; ""Non-thyroid illness ('sick euthyroid' syndrome)""; ""Transport and metabolism of thyroid hormones""; ""Biochemical measurements of thyroid hormone status""; ""Thyroid growth""; ""Nodular thyroid disease""; ""Thyroid cancer""; ""Clinical case questions""

""4. The adrenal gland""

Notes:

Includes index.

ISBN:

0-429-20595-3

1-280-24123-3

9786610241231

0-203-45043-4

9780429205958

OCLC:

1000432059