The development of science-based guidelines for laboratory animal care : proceedings of the November 2003 international workshop / Institute for Laboratory Animal Research, Division of Earth and Life Studies ; National Research Council of the National Academies.

Format:

Book

Conference/Event

Contributor:

Institute for Laboratory Animal Research (U.S.)

Conference Name:

International Workshop on the Development of Science-Based Guidelines for Laboratory Animal Care (2003 : Washington, D.C.)

Language:

English

Subjects (All):

Laboratory animals--Congresses.

Laboratory animals.

Biological laboratories--Management--Standards--Congresses.

Biological laboratories.

Physical Description:

1 online resource (xiv, 248 pages) : illustrations

Edition:

1st ed.

Other Title:

Science-based guidelines for laboratory animal care

Place of Publication:

Washington, D.C. : National Academies Press, c2004.

Language Note:

English

Summary:

The Development of Science-based Guidelines for Laboratory Animal Care is the summary of an international workshop held in Washington, DC, in November 2003 to bring together experts from around the world to discuss the available knowledge that can positively influence current and pending guidelines for laboratory animal care, identify gaps in that knowledge in order to encourage future research endeavors, and discuss the scientific evidence that can be used to assess the benefits and costs of various regulatory approaches affecting facilities, research, and animal welfare.

Contents:

FrontMatter

Preface

Contents

Introduction

Building the Case for Science-based Guidelines-Introductory Remarks

Hilton J. Klein

Plenary Lecture

Genes, Environments, and Mouse Behavior

John C. Crabbe

Session 1 Current Status: Identifying the Issues

AAALAC International Perspective

John G. Miller

The Council of Europe: What Is It?

Wim deLeeuw

ICLAS and the International Community

Gilles Demers

Role of the National Institutes of Health Office of Laboratory Animal Welfare and the Public Health Service Policy on Humane Care and Use of Laboratory Animals

Nelson L. Garnett

Regulatory Authority of the US Department of Agriculture Animal and Plant Health Inspection Service

Chester A. Gipson

A Review and Comparison of Processes to Change Regulatory Guidelines: A European Perspective

Jonathan Richmond

Japanese Regulations on Animal Experiments: Current Status and Perspectives

Naoko Kagiyama and Tatsuji Nomura

Process for Change-Development and Implementation of Standards for Animal Care and Use in Canada

Clément Gauthier

Building Credible Science from Quality, Animal-based Information

Paul Gilman

Session 2 Assessment of Animal Housing Needs in the Research Setting- Peer-reviewed Literature Approach

Disruption of Laboratory Experiments Due to Leaching of Bisphenol A from Polycarbonate Cages and Bottles and Uncontrolled Variability in Components of Animal Feed

Frederick S. vom Saal, Catherine A. Richter, Rachel R. Ruhlen, Susan C. Nagel, and Wade V. We

Assessment of Animal Housing Needs in the Research Setting Using a Peer-reviewed Literature Approach: Dogs and Cats

Graham Moore

Housing for Captive Nonhuman Primates: The Balancing Act

Melinda Novak

Assessment of Animal Housing Standards for Rabbits in a Research Setting

Markus Stauffacher and Vera Baumans.

Session 3 Approaches to Current Guidelines- United States and Europe

Housing Standards: Development of Guidelines and the Process for Change

William J. White

Revision of Appendix A to the European Convention ETS 123: The Participants, the Process, and the Outcome

Derek Forbes

Breakout Session: Rats and Mice

Effects of Housing Density and Cage Type on Young Adult C57BL/6J Mice

New Housing Standards for Rats and Mice Developed with Focus on the Needs of the Animals

Breakout Session: Approaches for Implementing Current US and European Guidelines for Housing Standards for Dogs and Cats

Breakout Session: Nonhuman Primates

Breakout Session: Rabbit Housing

Session 4 Environmental Control for Animal Housing

Environmental Controls (US Guidance)

Bernard Blazewicz and Dan Frasier

European Guidelines for Environmental Control in Laboratory Animal Facilities

Harry J. M. Blom

Breakout Session: Lighting

Breakout Session: Effects of Sound on Research Animals

Breakout Session: Environmental Control for Animal Housing- Impact on Metabolism and Immunology

Breakout Session: Environmental Control/ Engineering Issues

Dinner Speaker

Kay E. Holekamp

A View from the Field: What the Lives of Wild Animals Can Teach Us About Care of Laboratory Animals

Session 5 Environmental Enrichment Issues

Enriching the Housing of the Laboratory Rodent: How Might It Affect Research Outcomes?

William T. Greenough and Ann Benefiel

Search for Optimal Enrichment

Timo Nevalainen

Breakout Session: Environmental Enrichment Issues: Mice/Rats/Rabbits

Breakout Session: Environmental Enrichment for Dogs and Cats

Breakout Session: Assessment of Nonhuman Primate Enrichment- Science Versus Welfare Concerns

Point/Counterpoint: The Cases For and Against Harmonization.

Point/Counterpoint: The Cases For and Against Harmonization

William S. Stokes

Appendixes

Appendix A: International Workshop on Development of Science-based Guidelines for Laboratory Animal Care

Appendix B: Workshop Faculty

Appendix C: Committee Bios

Appendix D: International Guiding Principles for Biomedical Research Involving Animals (1985).

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references.

ISBN:

9786610175888

9780309165549

0309165547

9781280175886

1280175885

9780309545327

0309545323

OCLC:

57743594