Biomedical chemistry : current trends and developments / Nuno Vale ; managing editor, Anna Rulka ; language editor, Reuben Hudson & Michael Jones.

Format:

Book

Author/Creator:

Vale, Nuno, author.

Contributor:

Rulka, Anna, editor.

Hudson, Reuben, editor.

Jones, Michael, editor.

Language:

English

Subjects (All):

Pharmaceutical chemistry.

Physical Description:

1 online resource (361 pages) : illustrations, tables

Edition:

1st ed.

Place of Publication:

Berlin, [Germany] : De Gruyter Open, 2015.

Language Note:

In English.

Summary:

Biomedical Chemistry provides readers with an understanding of how fundamental chemical concepts are used to combat some diseases. The authors explain the interdisciplinary relationship of chemistry with biology, physics, pharmacy and medicine. The results of chemical research can be applied to understand chemical processes in cells and in the body, and new methods for drug transportation. Also, basic chemical ideas and determination of disease etiology are approached by developing techniques to ensure optimum interaction between drugs and human cells. This Book is an excellent resource for students and researchers in health-related fields with frontier topics in medicinal and pharmaceutical chemistry, organic chemistry and biochemistry.

Contents:

Front matter

Contents

Preface

Section 1: Chemical Principles in Drug Design and Discovery

1.1 Functional Groups of Biomolecules and their Reactions / Pinto, Diana C. G. A. / Pereira, João M. P. / Silva, Artur M. S.

1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge / Lopes, Francisca / Santos, Maria M. M. / Moreira, Rui

Section 2: Chemical Basis of Drug Action and Diseases

2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development / Fortuna, Ana / Alves, Gilberto / Falcão, Amílcar

2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression / Wong, Ma-Li / Lewis, Martin / Licinio, Julio

2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile / Pereira, Cidália / Monteiro, Rosário / João Martins, Maria

2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems / Lobo, Andrea / Summavielle, Teresa

Section 3: Strategies to Develop New and Better Drugs

3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? / Vale, Nuno

3.2 Targeting Calcium-mediated Excitotoxicity in the CNS / Chambers, James J.

3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs / Fransson, Rebecca / Sköld, Christian / Sandström, Anja

3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease / Pybus, Brandon S.

3.5 Current Trends and Developments for Nanotechnology in Cancer / Ferreira, Mónica / Almeida, Patrick / Shahbazi, Mohammad-Ali / Correia, Alexandra / Santos, Hélder A.

Index

Notes:

Includes bibliographical references and index.

This eBook is made available Open Access. Unless otherwise specified individually in the content, the work is licensed under the Creative Commons Attribution-Non Commercial-No Derivatives (CC BY-NC-ND) license: https://creativecommons.org/licenses/by-nc-nd/3.0 https://www.degruyter.com/dg/page/open-access-policy

Description based on online resource; title from PDF title page (ebrary, viewed February 9, 2016).

ISBN:

9783110468755

3110468751

9783110468878

3110468875

OCLC:

939265274