1 option
Dendritic spines : from shape to function / edited by Nicolas Heck and Ruth Benavides-Piccione.
- Format:
- Book
- Author/Creator:
- Nicolas Heck
- Series:
- Frontiers Research Topics
- Language:
- English
- Subjects (All):
- Dendrites.
- Pyramidal cell.
- Cerebral cortex.
- Synapses.
- Physical Description:
- 1 online resource (235 pages) : illustrations.
- Other Title:
- Dendritic spines
- Place of Publication:
- Frontiers Media SA 2016
- France : Frontiers Media SA, 2016
- Language Note:
- English
- System Details:
- text file
- Summary:
- One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dendrite reflects the levels of connectivity within the neuronal network. Furthermore, the relevance of studying dendritic spines is emphasized by the observation that their morphology changes with synaptic plasticity and is altered in many psychiatric disorders. The present Research Topic deals with some of the most recent findings concerning dendritic spine structure and function, showing that, in order to understand how brain neuronal activity operates, these two factors should be regarded as being intrinsically linked.
- Notes:
- Includes bibliographical references.
- Creative Commons NonCommercial-NoDerivs https://creativecommons.org/licenses/http://journal.frontiersin.org/researchtopic/1533/dendritic-spines-from-shape-to-function
- Description based on online resource ; title from PDF title page (viewed on 03/14/2021)
- ISBN:
- 9782889197668 (ebook)
- Access Restriction:
- Unrestricted online access
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.