Resource sharing in biomedical research / Committee on Resource Sharing in Biomedical Research, Division of Health Sciences Policy, Institute of Medicine ; Kenneth I. Berns, Enriqueta C. Bond, and Frederick J. Manning, editors.

Format:

Book

Author/Creator:

Institute of Medicine (U.S.). Committee on Resource Sharing in Biomedical Research.

Contributor:

Berns, Kenneth I., 1938-

Bond, Enriqueta C.

Manning, Frederick J.

Language:

English

Subjects (All):

Medicine--Research--United States.

Medicine.

Medical research personnel--United States.

Medical research personnel.

Physical Description:

viii, 96 p. : ill.

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1996.

Language Note:

English

Summary:

The United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research.

Contents:

Intro

Copyright

Preface

Contents

Executive Summary

CASE STUDIES

The American Type Culture Collection

The Multinational Coordinated Arabidopsis Thaliana Genome Research Project

The Jackson Laboratory

The Washington Regional Primate Research Center

The Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source

The Human Genome Center at Lawrence Livermore National Laboratory

CONCLUSIONS AND RECOMMENDATIONS

Features of Successful Resource Sharing

Strong Scientific Leadership in Agencies and the Research Community

Adequate Core Funding

Marketing and Advertising

Clear Guidelines about Ownership and Access

User Fees

Clear Policies for Retaining and Discarding Data and Material

Quality Control

Well-Defined Policies for Function of Research and Service at the Facility

Sophisticated Information Retrieval and Transfer Systems

Issues and Problems

One Uniform Policy on Resource Sharing is Not Possible

Incentives and Rewards for Resource Sharing are Not Fully Developed

Methods for Enforcing Existing Policies on Resource Sharing are Inadequate

There are Many Private and Public Stakeholders in Any Major Resource Sharing Attempt, Often with Conflicting Goals

Who Pays and What Do They Pay for?

Regulatory Requirements and Documentation Can Be Unnecessarily Complex and Burdensome

Education of Scientists Covers Neither the Ethos of Sharing Nor Intellectual and Tangible Property Issues

Resource Sharing Can Have National and International Implications

There is a Gap in Leadership

Partnerships in Resource Sharing May Be Unequal

Monopolies Can Be Good or Bad

RECOMMENDATIONS

1 Introduction

COMPETITION FOR FUNDS

INCENTIVES FOR SCIENTISTS

NATIONALISM

METHODS AND GOALS OF THIS STUDY

A Member Survey

The Committee.

The Workshop

The Report and Its Recommendations

REFERENCES

2 The American Type Culture Collection

GENERAL FACILITIES

PROGRAMS

Collection, Research, and Services Program

Professional Services Program

Education Services Program

Information Services Program

OWNERSHIP AND ACCESS ISSUES

COST ISSUES

OTHER ISSUES AND PROBLEMS

3 The Multinational Coordinated Arabidopsis Thaliana Genome Research Project

PROJECT ELEMENTS

4 The Jackson Laboratory

ANIMAL RESOURCE PROGRAMS

Production, Sale, Derivation, and Maintenance of Mice

Preservation

Derivation

Surgery

Bioinformatics

5 The Washington Regional Primate Research Center

FACILITIES AND PROGRAMS

6 The Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source

USER FACILITIES FOR PROTEIN CRYSTALLOGRAPHY AT SYNCHROTRONS

THE MACCHESS RESEARCH RESOURCE

Core Research Projects

Collaborative Research Projects

User Research Projects (Service)

Training and Dissemination

Workshops and Symposia

Training Videos

CHESS Newsletter

MacCHESS World Wide Web (WWW) Home Page

7 The Human Genome Center: Lawrence Livermore National Laboratory

LAWRENCE LIVERMORE NATIONAL LABORATORY

HUMAN GENOME CENTER

Instrumentation and Technology

Information

Biological Materials

Chromosome 19-Specific Cosmids

Image Consortium cDNA Clones

SUMMARY OF ISSUES AND PROBLEMS

8 Conclusions and Recommendations

FEATURES OF SUCCESSFUL RESOURCE SHARING.

Strong Scientific Leadership in Agencies and the Research Community

ISSUES AND PROBLEMS

Sharing Requires Incentives, Not Disincentives

The Importance of Material and Data Assets Changes Over Time

Technologies and Needs are Evolving Very Rapidly

New Definitions of "Publication" May Have to Evolve to Keep Pace with the New Electronic Information Systems

Methods for Enforcing Existing Policies on Sharing are Inadequate

There are Many Private and Public Stakeholders in any Major Resource Sharing Attempt, Often With Conflicting Goals

Partnerships in Sharing Resources May Be Unequal

Appendix A Workshop on Resource Sharing in Biomedical Research

Appendix B Acronyms.

Notes:

"Report on a workshop, held in Washington, D.C., January 22-23, 1996"--Pref.

Includes bibliographical references.

ISBN:

9786610192021

9781280192029

128019202X

9780309589659

0309589657

9780585154640

0585154643

OCLC:

923262262