Colloquium on genetic engineering of viruses and viral vectors / Proceedings of the National Academy of Sciences.

Format:

Book

Author/Creator:

Proceedings of the National Academy of Sciences.

Language:

English

Subjects (All):

Immunology.

Genetics.

Physical Description:

1 online resource (141 pages)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academies Press, 1997.

Language Note:

English

Contents:

""PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA""; ""Contents""; ""Genetic engineering of viruses and of virus vectors: A preface""; ""Site-specific integration by adeno-associated virus""; ""Oncogenic potential of the adenovirus E4orf6 protein""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""The function of herpes simplex virus genes: A primer for genetic engineering of novel vectors""

""Genome Structure and Gene Content""" "The Role of Selected Viral Genes in Viral Replication""; ""The Function of Viral Genes in Latency""; ""Genetic Engineering of Novel Viral Genomes""; ""Requirements and Design of Viral Vectors""; ""Conclusions""; ""The application of genetically engineered herpes simplex viruses to the treatment of experimental brain tumors""; ""Direct Virus Therapy""; ""Conclusion""; ""Replication-defective herpes simplex virus vectors for gene transfer in vivo""

""A deletion mutant in the human cytomegalovirus gene encoding IE1491aa is replication defective due to a failure in """"MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Epstein-Barr virus vectors for gene delivery to B lymphocytes""; ""MATERIALS AND METHODS""; ""RESULTS AND DISCUSSION""; ""Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety""

""Applications of pox virus vectors to vaccination: An update"" ""Vaccinia-Rabies Glycoprotein G Recombinant""; ""Fowlpox Virus-Based Recombinants""; ""Avipox Virus Vectors in Nonavian Species""; ""Attenuated Vaccinia-Based Vector: NYVAC""; ""Other Applications of Pox Virus-Based Vectors""; ""Discussion""; ""Negative-strand RNA viruses: Genetic engineering and applications""; ""DNA-Containing Viruses""; ""Positive-Strand RNA Viruses""; ""Introduction of cDNA-Derived RNA into a Negative-Strand RNA Virus (Influenza Virus)""; ""Plasmid-Based Reverse Genetics System for Influenza Virus""

""Chimeric Influenza Viruses Expressing Foreign Epitopes or Polypeptides"" ""Rescue of Infectious Rabies Virus from cDNA""; ""Rescue of Other Nonsegmented Negative-Strand RNA Viruses""; ""Perspective""; ""Foreign glycoproteins expressed from recombinant vesicular stomatitis viruses are incorporated efficiently into virus�""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Specific infection of CD4+ target cells by recombinant rabies virus pseudotypes carrying the HIV-1 envelope spike protein""; ""MATERIALS AND METHODS""; ""RESULTS""; ""DISCUSSION""; ""Alphavirus-based expression vectors: Strategies and applications""

Notes:

Description based upon print version of record.

ISBN:

1-280-18707-7

9786610187072

0-309-56897-8

OCLC:

923269982