Biomedical models and resources : current needs and future opportunities / Committee on New and Emerging Models in Biomedical and Behavioral Research, Institute for Laboratory Animal Research, Commission on Life Sciences, National Research Council.

Format:

Book

Contributor:

Institute for Laboratory Animal Research (U.S.). Committee on New and Emerging Models in Biomedical and Behavioral Research.

Language:

English

Subjects (All):

Animal experimentation--United States.

Animal experimentation.

Medicine--Research--United States.

Medicine.

Animal models in research--United States.

Animal models in research.

National Center for Research Resources (U.S.).

Physical Description:

1 online resource (84 p.)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1998.

Language Note:

English

Contents:

Biomedical Models and Resources

Copyright

Preface

Contents

Executive Summary

1 Introduction

THE COMMITTEE'S CHARGE AND APPROACH

STRUCTURE OF THE REPORT

2 Biomedical Model Definition

3 Essential and Emerging Research Fields and Technologies

FUNCTIONAL GENOMICS

AGING

BEHAVIOR AND NEUROBIOLOGY

COMPLEX DISEASE

MODEL DISCOVERY

MATHEMATICAL MODELLING, COMPUTATIONAL SIMULATIONS, AND SCIENTIFIC DATABASES

EMERGING AND RE-EMERGING INFECTIOUS DISEASES

4 Overriding Issues

ISSUES WITHIN THE PURVIEW OF NCRR

MAINTENANCE AND PRESERVATION

FACILITY INFRASTRUCTURE

AVAILABILITY OF EXPERTISE AND TRAINING

INFECTIOUS DISEASE, ANIMAL HEALTH

ISSUES BEYOND THE SCOPE OF NCRR

CIRCULAR A-21

INTELLECTUAL PROPERTY RIGHTS

DATABASES AND CONFIDENTIALITY

5 Recommendations

ENCOURAGE AND SUPPORT RESEARCH DIRECTED AT IMPROVING RESEARCH ANIMALUTILITY, AVAILABILITY, HEALTH, WELFARE, AND MAINTENANCE

LABORATORY ANIMAL HEALTH AND WELFARE

Diagnosis and infectious disease

Behavior

IMPROVED ANIMAL ACQUISITION, MAINTENANCE, PROPAGATION AND PRESERVATION

DEVELOPMENT OF GENETIC MAPS FOR ADDITIONAL MODEL SPECIES

INSTRUMENTATION DEVELOPMENT AND MINIATURIZATION

CREATE A NATIONAL NETWORK OF COMPARATIVE MEDICAL EXPERTISE

TO SUPPORT NIH RESEARCH EFFORTS ON ANIMAL MODELS, SUCH AS PHENOTYPICAND GENOTYPIC ASSESSMENT AND DISEASE DIAGNOSTICS

TO PROMOTE MULTIDISCIPLINARY INTERACTION

CREATE A NATIONAL NETWORK OF INTEGRATIVE-BIOLOGY EXPERTISE THAT CANSERVE THE ENTIRE BIOMEDICAL RESEARCH COMMUNITY

ACADEMIC INFRASTRUCTURE FOR INTEGRATIVE BIOLOGY RELATED TO ANIMALS

Encouragement and Facilitation of Interdisciplinary Research

Development and Dissemination of Appropriate Information Technologies.

Development and Maintenance of Databases, Interdisciplinary Modelling and Informatics Issues. The Si ...

INCREASE THE COMMITMENT AND RESOURCES FOR CONSTRUCTING AND RENOVATINGANIMAL RESEARCH FACILITIES

REINVIGORATE AND EXPAND TRAINING OPPORTUNITIES IN INTEGRATIVE BIOLOGY

OBTAIN PROGRAM GUIDANCE FROM THE SCIENTIFIC COMMUNITY

USE EXISTING MECHANISMS BETTER

FUND INDEPENDENT EXTERNAL ADVISORY GROUPS EVERY FOUR YEARS

6 Criteria

References

APPENDIXES

APPENDIX A SURVEY INSTRUMENT

Future Trends in Biomedical Research

BIOMEDICAL MODELS FOR THE NEXT 5-10 YEARS

CURRENT MODELS WAITING TO BE DEVELOPED

IDENTIFYING NEW BIOLOGICAL MODELS

APPENDIX B BIOGRAPHICAL SKETCHES OF AUTHORING COMMITTEE

WORKSHOPAGENDA

AND WORKSHOP PARTICIPANTS

APPENDIX C Models for Biomedical Research

What Is a Model?

REFERENCES

APPENDIX D COMPARATIVE MEDICAL SCIENTISTS' REPORT

A. Biotechnology

B. Specialized Facilities

C. Diagnostics

D. Informatics

E. Training

F. Administration

G. Personnel

H. Facilities.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references.

ISBN:

9786610186808

9781280186806

1280186801

9780309569965

0309569966

9780585182131

0585182132

OCLC:

44964138