Health effects of exposure to low levels of ionizing radiations : time for reassessment? / Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations, Board on Radiation Effects Research, Commission on Life Sciences, National Research Council.

Format:

Book

Contributor:

National Research Council (U.S.). Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations.

Series:

BEIR (Series) ; 7.

Compass series (Washington, D.C.)

BEIR ; 7

The Compass series

Language:

English

Subjects (All):

Low-level radiation--Health aspects.

Low-level radiation.

Physical Description:

1 online resource (86 p.)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1998.

Language Note:

English

Summary:

The US Environmotection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment.

Contents:

Health Effects of Exposure to Low Levels of Ionizing Radiations

Copyright

Preface

Contents

EXECUTIVE SUMMARY

1 INTRODUCTION

2 EPIDEMIOLOGIC INVESTIGATIONS

NEW EPIDEMIOLOGIC RESULTS

ADVANCES IN METHODOLOGY

CONSIDERATIONS FOR A BEIR VII PHASE-2 COMMITTEE

RADIOEPIDEMIOLOGIC TABLES

3 CELLULAR AND MOLECULAR CONSIDERATIONS

DNA DAMAGE AND ITS REPAIR

CONCLUSIONS

CONDITIONED AND INDUCIBLE RESPONSES TO RADIATION

CHROMOSOMAL ABERRATIONS AND MUTATIONS

Chromosomal Aberrations

Mutations

4 ANIMAL STUDIES

5 RADIOBIOLOGIC PRINCIPLES AND RISK MODELING

LINEARITY VERSUS CURVILINEARITY

THE DOSE DEPENDENCE OF RBE

POTENTIAL IMPACT OF NEUTRONS

6 MATHEMATICAL MODELS OF RADIATION CARCINOGENESIS

THE TWO-MUTATION MODEL

IMPLICATIONS OF THE MODEL FOR RISK ESTIMATION

LITERATURE CITED

Information on Committee Members

List of Acronyms

ACKNOWLEDGMENTS.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references (p. 51-72) and index.

ISBN:

9786610186457

9780309173797

0309173795

9781280186455

1280186453

9780309580526

0309580528

9780585155760

0585155763

OCLC:

44964205