Definition of pain and distress and reporting requirements for laboratory animals : proceedings of the workshop held June 22, 2000 / Committee on Regulatory Issues in Animal Care and Use, Institute for Laboratory Animal Research, National Research Council.

Format:

Book

Conference/Event

Contributor:

National Research Council (U.S.). Committee on Regulatory Issues in Animal Care and Use.

Conference Name:

Workshop on Definition of Pain and Distress and Reporting Requirements (2000 : Washington, D.C.)

Workshop on Definition of Pain and Distress and Reporting Requirements for Laboratory Animals

Series:

Compass series (Washington, D.C.)

Compass series

Language:

English

Subjects (All):

Laboratory animals--Health--Congresses.

Laboratory animals.

Laboratory animals--Health.

Laboratory animals--Effect of stress on--Congresses.

Laboratory animals--Effect of stress on.

Laboratory animals--Law and legislation--United States--Congresses.

Laboratory animals--Law and legislation--United States.

Animal experimentation--Law and legislation--United States--Congresses.

Animal experimentation.

Animal experimentation--Law and legislation--United States.

Physical Description:

1 online resource (xii, 119 pages)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, c2000.

Language Note:

English

Summary:

In this first in a proposed series of workshops on regulatory issues in animal care and use, the Institute for Laboratory Animal Research (ILAR) has addressed the existing and proposed requirements for reporting pain and distress in laboratory animals. The Animal Welfare Act, administered by the Animal and Plant Health Inspection Service of the United States Department of Agriculture (USDA), mandates that pain and distress in laboratory animals be minimized. USDA is considering two policy changes with regard to this specific mandate. Firstly, since there has been no functional definition of "distress," USDA has prepared such a definition and requested feedback from the scientific community on its usefulness for regulatory and reporting requirements. The second issue concerns the pain and distress categorization scheme for reporting to USDA. Various groups and individuals have questioned the efficacy of the current categories, and specific changes have been proposed by the Humane Society of the United States. USDA is considering these and other potential changes to the existing scheme. Thus, given these potential changes to animal welfare policy, the aim of the ILAR/NIH joint workshop was to provide feedback to the USDA. The speakers were asked to address these two issues as well as to comment upon whether the information contained in the 1992 ILAR report Recognition and Alleviation of Pain and Distress in Laboratory Animals is still useful to investigators in assisting them to comply with regulations. The speakers provided perspectives based on their individual expertise in the areas of science of pain and distress, animal welfare policy, protocol review, and/or as representatives of relevant organizations or institutions. The following proceedings are an edited transcript of their presentations.

Contents:

""DEFINITION OF PAIN AND DISTRESS AND REPORTING REQUIREMENTS FOR LABORATORY ANIMALS""; ""Copyright""; ""Preface""; ""Contents""; ""Introduction""; ""REFERENCE""; ""Pain and Distress: USDA Perspective""; ""POLICY 12""; ""POLICY 11""; ""EXPLANATION OF CATEGORIES""; ""Column C""; ""Column D""; ""Column E""; ""DISCUSSION""; ""Pain, Distress, and Reporting Requirements: PHS Policy Perspective""; ""INTERRELATED ISSUES""; ""Similarity of Initiatives""; ""RATS, MICE, AND BIRDS""; ""HSUS PAIN AND DISTRESS INITIATIVE""; ""CONCLUSION""; ""REFERENCE""

""Assessing Pain and Distress: A Veterinary Behaviorist's Perspective""; ""ASSESSING PAIN AND DISTRESS""; ""The Dilemma of Definitions""; ""Issues with Assessing Pain""; ""Issues with Assessing Distress""; ""Indicators of Pain""; ""Indicators of Distress""; ""Degrees of Stress""; ""Using Behavior to Assess Pain and Distress""; ""A Program of Pain and Distress Management""; ""REFERENCES""; ""QUESTIONS AND ANSWERS""; ""Scientific Issues of Pain and Distress""; ""PAIN VERSUS NOCICEPTION""; ""Pain""; ""Nociception""; ""Noxious Stimuli""; ""CLASSIFICATIONS OF PAIN""; ""Protective Pain""

""Nonprotective Pain""; ""TISSUE INJURY""; ""Sensitization""; ""Hyperalgesia""; ""STRESS AND DISTRESS""; ""Definition of Terms""; ""Reduction with Preemptive Analgesia""; ""CONCLUSION""; ""REFERENCES""; ""QUESTIONS AND ANSWERS""; ""The Humane Society of the United States Pain and Distress Initiative""; ""CONTEXT OF THE INITIATIVE""; ""DEFINITIONS OF TERMS""; ""ASSESSING DISTRESS""; ""CONCLUSIONS""; ""REFERENCES""; ""QUESTIONS AND ANSWERS""; ""Pain and Distress Caused by Experimental Procedures: Is It Time for a Reality Check?""; ""UP-FRONT REPORTING""; ""Predictability""

""Planning for Optimal Animal Care""; ""CATEGORY D""; ""PLANNING EXPERIMENTAL METHODS""; ""SCIENTIFIC JOURNAL REPORTING""; ""SUMMARY""; ""REFERENCES""; ""A View from the Trenches""; ""WHO I AM""; ""HOW I GOT HERE""; ""WHY I CANNOT SUPPORT CHANGES IN THE EXISTING POLICY""; ""WASTING OUR FISCAL AND HUMAN RESOURCES""; ""REFERENCE""; ""QUESTIONS AND ANSWERS""; ""AALAS Position Paper on the Recognition and Alleviation of Pain and Distress in Laboratory Animals""; ""EVALUATING PAIN AND DISTRESS""; ""REPORTING ANIMAL USE""; ""ALLEVIATING PAIN AND DISTRESS""; ""TRAINING OF PERSONNEL""

""ROLES OF THE VETERINARIAN, IACUC, AND INVESTIGATOR""; ""REFINEMENT""; ""CONCLUSION""; ""QUESTIONS AND ANSWERS""; ""On Regulating Pain and Distress""; ""BENEFIT THE ANIMALS""; ""KEEP IT SIMPLE""; ""ETHICAL ISSUES""; ""QUESTIONS AND ANSWERS""; ""An Industrial Perspective""; ""SOURCES OF PAIN""; ""ASSESSMENT""; ""SHARED RESPONSIBILITY""; ""Institutions""; ""Investigators""; ""IACUC""; ""Veterinarians""; ""PAIN AND DISTRESS INITIATIVES""; ""HSUS""; ""USDA""; ""REPORTING""; ""Categorization""; ""CONCLUSION""; ""REFERENCES""; ""QUESTIONS AND ANSWERS""; ""Corners Still Unswept""; ""INTRODUCTIONS""; ""My Life as a Rat""

Notes:

"This study was supported by Grant No. N01-0D-4-2139 between the National Academies and the National Institutes of Health of the U.S. Department of Health and Human Services"--T.p. verso.

"Committee on Regulatory Issues in Animal Care and Use, Institute for Laboratory Animal Research, National Research Council."

Includes bibliographical references.

ISBN:

9786610185146

9780309171281

0309171288

9781280185144

1280185147

9780309565059

0309565057

OCLC:

923269086