Education and training in the care and use of laboratory animals : a guide for developing institutional programs / Committee on Educational Programs in Laboratory Animal Science, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council.

Format:

Book

Contributor:

Institute of Laboratory Animal Resources (U.S.). Committee on Educational Programs in Laboratory Animal Science.

Language:

English

Subjects (All):

Laboratory animals.

Animal welfare.

Physical Description:

1 online resource (151 pages)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1991.

Language Note:

English

Summary:

Guidelines and resources for instituting the training required by federal law. Annotation copyright Book News, Inc. Portland, Or.

Contents:

Education and Training in the Care and Use of Laboratory Animals

Copyright

Preface

Contents

I INTRODUCTION

1 Introduction

Reference

2 How to Use this Guide

II COURSE MODULES

1 Core Module

INTRODUCTION

OUTLINE FOR THE CORE MODULE

Laws, Regulations, and Policies that Impact on the Care and Use of Animals

Ethical and Scientific Issues

Alternatives

Responsibilities of the Institution, the Animal Care and Use Committee, and the Research and Veterinary Staffs

Pain and Distress

Anesthetics, Analgesics, Tranquilizers, and Neuromuscular Blocking Agents

Survival Surgery and Postsurgical Care

Euthanasia

Husbandry, Care, and the Importance of the Environment

Resources

2 Species-Specific Module

OUTLINE FOR THE SPECIES-SPECIFIC MODULE

Selection and Procurement of Animals

Husbandry and Care

Handling and Restraint

Identification and Records

Animal Health

Safety and Health Considerations (Zoonoses)

Specific Techniques

Skill Building

3 Pain-Management Module

OUTLINE FOR THE PAIN-MANAGEMENT MODULE

Definitions, Mechanisms, and Assessment

Legal and Ethical Obligations

Alleviation of Pain or Distress

Anesthesia

4 Surgery Module

OUTLINE FOR THE SURGERY MODULE

Definitions

Legal Requirements for Survival Surgery

Aseptic Technique

Selection and Administration of Anesthetic

Surgical Complications

Surgical Techniques

Postsurgical Care

Medical Records

Terminal Surgeries

III CONTENT OUTLINES

Introduction

1 Laws, Regulations, and Policies That Impact on the Care and Use of Animals

1.1 FEDERAL REGULATIONS AND POLICIES AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION.

1.2 SELECTED REQUIREMENTS OF AWRS AND PHS POLICY

1.3 STATE AND LOCAL REGULATIONS AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION…

1.4 INSTITUTIONAL POLICIES AFFECTING THE CARE AND USE OF ANIMALS IN RESEARCH, TESTING, AND EDUCATION

REFERENCES

2 Ethical and Scientific Issues

2.1 DEFINITIONS

2.2 CONCEPTUAL FRAMEWORK FOR ETHICAL DECISIONS (ROBB, 1989)

2.3 ARGUMENTS USED BY THOSE ADVOCATING THE HUMANE USE OF ANIMALS FOR HUMAN PURPOSES (CAPLAN, 1984)

2.4 ARGUMENTS USED BY ANIMAL-RIGHTS ADVOCATES (SINGER, 1975

REGAN, 1983)

2.5 THE ROLE OF LAWS, REGULATIONS, AND POLICIES

2.6 SUGGESTED ETHICAL PRINCIPLES (SEE U.S. GOVERNMENT PRINCIPLES FOR THE UTILIZATION AND CARE OF VERTEBRATE ANIMALS USED IN…

3 Alternatives

3.1 DEFINITIONS

3.2 RATIONALE FOR CONSIDERING ALTERNATIVES

3.3 NONANIMAL RESEARCH METHODS AND MODELS

3.4 FACTORS INFLUENCING MODEL SELECTION

3.5 UTILIZATION OF SERVICES

4 Responsibilities of the Institution, the Animal Care and Use Committee, and the Research and Veterinary Staffs

4.1 RESPONSIBILITIES OF THE INSTITUTION

4.2 RESPONSIBILITIES OF THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC)

4.3 RESPONSIBILITIES OF THE INVESTIGATOR (THE TERM INVESTIGATOR IS USED BROADLY TO DESIGNATE THOSE PEOPLE RESPONSIBLE…

4.4 RESPONSIBILITIES OF THE ATTENDING VETERINARIAN (SEE 9 CFR 2.33)

5 Pain and Distress

5.1 DEFINITIONS

5.2 CATEGORIES OF PAIN (AVMA, 1986)

5.3 PAIN PERCEPTION

5.4 ASSESSMENT OF PAIN (AVMA, 1986)

5.5 STRESS (NRC, IN PRESS)

5.6 DISTRESS (NRC, IN PRESS)

5.7 ETHICAL OBLIGATIONS

5.8 LEGAL OBLIGATIONS (OVERSEEN BY THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE)

5.9 ADEQUATE VETERINARY CARE

6 Anesthetics, Tranquilizers, Analgescis, and Neuromuscular Blocking Agents.

6.1 GENERAL ANESTHETICS (LUMB AND JONES, 1984)

6.2 TRANQUILIZERS AND SEDATIVES (GLEED, 1987)

6.3 Analgesics

6.4 NEUROMUSCULAR BLOCKING AGENTS (PARALYTICS OR IMMOBILIZING AGENTS)

6.5 FACTORS MODIFYING THE EFFECTS OF TRANQUILIZERS, ANALGESICS, AND NEUROMUSCULAR BLOCKING AGENTS

6.6 SAFETY PRECAUTIONS

6.7 RECORDKEEPING REQUIREMENTS

6.8 FUNCTIONS OF THE ATTENDING VETERINARIAN IN PAIN MANAGEMENT

7 Survival Surgery and Postsurgical Care

7.1 DEFINITIONS

7.2 LEGAL REQUIREMENTS (9 CFR 2.31

PHS, 1986)

7.3 PREPARATION FOR SURGERY

7.4 ANESTHESIA (SEE SECTION 6.1)

7.5 SURGICAL COMPLICATIONS

7.6 INCISIONS

7.7 POSTSURGICAL CARE

7.8 EQUIPMENT: TYPE NEEDED TO PROPERLY SUPPORT SURGICAL PROCEDURES IS DEPENDENT ON A NUMBER OF VARIABLES, INCLUDING THE…

7.9 RECORDKEEPING

8 Euthanasia

8.1 DEFINITION

8.2 LEGAL REQUIREMENTS

8.3 ETHICAL AND HUMANE CONSIDERATIONS

8.4 HUMAN CONSIDERATIONS

8.5 CRITERIA FOR SELECTION OF METHOD OF EUTHANASIA

8.6 Pharmacologic Methods

8.7 PHYSICAL METHODS

8.8 Carcass Disposal

9 Husbandry, Care, and the Importance of the Environment

9.1 LEGAL REQUIREMENTS FOR HUSBANDRY AND CARE

9.2 IMPORTANCE OF PROPER HUSBANDRY AND A STABLE ENVIRONMENT

9.3 ENVIRONMENTAL VARIABLES THAT CAN BE CONTROLLED

9.4 DEALING WITH EMERGENCIES (E.G., POWER FAILURE, FLOODING, AIR-HANDLINGFAILURE, HEATING OR COOLING FAILURE, FIRE

REFERENCE

10 Species-Specific Overview

Outline

10.1 FACTORS ASSOCIATED WITH SELECTION OF ANIMALS

10.2 PROCUREMENT OF ANIMALS

10.3 CAGING

10.4 ENVIRONMENTAL ENRICHMENT

10.5 FOOD

10.6 WATER

10.7 HANDLING AND RESTRAINT

10.8 IDENTIFICATION AND RECORDS

10.9 ANIMAL HEALTH

10.10 ZOONOSES (DESCRIBE SIGNS AND SYMPTOMS IN ANIMALS AND HUMANS).

10.11 SPECIFIC TECHNIQUES: HANDS-ON TRAINING IN TECHNIQUES SUCH AS BLOOD WITHDRAWAL, INJECTIONS, SPE ...

IV RESOURCES

1 Sources of Information

ANIMAL WELFARE INFORMATION CENTER

NATIONAL LIBRARY OF MEDICINE

INSTITUTE OF LABORATORY ANIMAL RESOURCES

FOUNDATION FOR BIOMEDICAL RESEARCH

CENTER FOR ALTERNATIVES

CENTER FOR ANIMALS AND PUBLIC POLICY

2 Selected Bibliography

LAWS, POLICIES, AND GUIDELINES

ETHICS, ANIMAL WELFARE, AND THE USE OF ANIMALS IN BIOMEDICAL RESEARCH, EDUCATION, AND TESTING

ALTERNATIVES

INSTITUTIONAL ANIMAL CARE AND USE COMMITTEES

RECOGNITION AND ALLEVIATION OF PAIN AND DISTRESS

SURGERY

EUTHANASIA

BIOLOGY, HUSBANDRY, AND CARE

General References (Concerning More than one Species or Subject)

Species-Specific References

Carnivores

Domestic Animals

Nonhuman Primates

Rabbits

Rodents

Other Animals

GENETICS AND NOMENCLATURE

NUTRITION

OCCUPATIONAL HAZARDS AND LABORATORY SAFETY

PATHOLOGY AND THERAPY

General References

Fishes

Rabbits and Rodents

OTHER ANIMALS

DESIGN OF EDUCATIONAL COURSES

3 Audiovisual Materials

V HOW TO DEVELOP, DELIVER, AND EVALUATE AN EDUCATIONAL PROGRAM

1 How to Approach the Task of Education

EDUCATIONAL GOALS

SETTING OBJECTIVES

SELECTING METHODS

Lectures/Seminars

Interactive Sessions

Workshops/Laboratories

Individualized Study

Self Assessment

OVERCOMING RESISTANCE TO CHANGE

CONCLUSIONS

2 How to Plan and Implement a Training Course

IDENTIFYING THE TARGET AUDIENCE

ALLOCATING A BUDGET/FUNDING

DETERMINING GOALS AND OBJECTIVES

SCHEDULING THE COURSE

RESERVING FACILITIES

IDENTIFYING AND CONTACTING LECTURERS

OBTAINING AND REVIEWING AUDIOVISUAL MATERIALS.

ASSEMBLING REFERENCE MATERIALS

PUBLICIZING THE COURSE

3 Evaluation

EVALUATING THE INSTITUTIONAL PROGRAM

EVALUATING THE COURSE

Appendixes

I Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training

II The Animal Welfare Information Center

ANIMAL WELFARE INFORMATION CENTER ESTABLISHED

SERVICES AND INFORMATION RESOURCES AVAILABLE THROUGH AWIC

AWIC REFERENCE PUBLICATIONS

PROJECTS SUPPORTED BY AWIC

UPDATES REGARDING AWIC AND NAL

PUBLICATIONS AVAILABLE THROUGH AWIC

III Sample Objectives or Self-Assessment Statements

CORE MODULE

Laws, Regulations, and Policies That Impact on the Care and Use of Animals

Responsibilities of the Institution, Animal Care and Use Committee, and Research and Veterinary Staffs

Survival Surgical and Postsurgical Care

SPECIES-SPECIFIC MODULE

PAIN-MANAGEMENT MODULE

Anesthestics

SURGERY MODULE

Animal Monitoring

Terminal Surgeries.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references (p. 89-102).

ISBN:

9786610212026

9781280212024

1280212020

9780309574631

0309574633

9780585028835

0585028834

OCLC:

559502158