Guide for the care and use of laboratory animals / Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council.

Format:

Book

Author/Creator:

Institute of Laboratory Animal Resources (U.S.).

Language:

English

Subjects (All):

Laboratory animals--Handling--United States.

Laboratory animals.

Animal welfare--United States.

Animal welfare.

Animal experimentation--United States.

Animal experimentation.

Physical Description:

1 online resource (140 pages)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1996.

Language Note:

English

Summary:

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and includes extensive references. It is organized around major components of animal use: Institutional policies and responsibilities. The committee discusses areas that require policy attention: the role and function of the Institutional Animal Care and Use Committee, protocols for animal care and use, occupational health and safety, personnel qualifications, and other areas. Animal environment, husbandry, and management. The committee offers guidelines on how to design and run a management program, addressing environment, nutrition, sanitation, behavioral and social issues, genetics, nomenclature, and more. Veterinary care. The committee discusses animal procurement and transportation, disease and preventive medicine, and surgery. The Guide addresses pain recognition and relief and issues surrounding euthanasia. Physical plant. The committee identifies design and construction issues, providing guidelines for animal-room doors, drainage, noise control, surgery, and other areas. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. This revision will be important to researchers, animal care technicians, facilities managers, administrators at research institutions, policymakers involved in research issues, and animal welfare advocates.

Contents:

Guide for the Care and Use of Laboratory Animals

Copyright

Note

Preface

Contents

Introduction

REGULATIONS, POLICIES, AND PRINCIPLES

EVALUATION CRITERIA

FARM ANIMALS

NONTRADITIONAL SPECIES

FIELD INVESTIGATIONS

OVERVIEW

REFERENCES

1 Institutional Policies and Responsibilities

MONITORING THE CARE AND USE OF ANIMALS

Institutional Animal Care and Use Committee

Animal Care and Use Protocols

Physical Restraint

Multiple Major Surgical Procedures

Food or Fluid Restriction

VETERINARY CARE

PERSONNEL QUALIFICATIONS AND TRAINING

OCCUPATIONAL HEALTH AND SAFETY OF PERSONNEL

Hazard Identification and Risk Assessment

Personnel Training

Personal Hygiene

Facilities, Procedures, and Monitoring

Animal Experimentation Involving Hazards

Personal Protection

Medical Evaluation and Preventive Medicine for Personnel

2 Animal Environment, Housing, and Management

PHYSICAL ENVIRONMENT

Microenvironment and Macroenvironment

Housing

Primary Enclosures

Sheltered or Outdoor Housing

Naturalistic Environments

Space Recommendations

Temperature and Humidity

Ventilation

Illumination

Noise

BEHAVIORAL MANAGEMENT

Structural Environment

Social Environment

Activity

HUSBANDRY

Food

Water

Bedding

Sanitation

Bedding Change

Cleaning and Disinfection of Primary Enclosures

Cleaning and Disinfection of Secondary Enclosures

Assessing the Effectiveness of Sanitation

Waste Disposal

Pest Control

Emergency, Weekend, and Holiday Care

POPULATION MANAGEMENT

Identification and Records

Genetics and Nomenclature

3 Veterinary Medical Care

ANIMAL PROCUREMENT AND TRANSPORTATION

PREVENTIVE MEDICINE

Quarantine, Stabilization, and Separation.

Surveillance, Diagnosis, Treatment, and Control of Disease

SURGERY

PAIN, ANALGESIA, AND ANESTHESIA

EUTHANASIA

4 Physical Plant

FUNCTIONAL AREAS

CONSTRUCTION GUIDELINES

Corridors

Animal-Room Doors

Exterior Windows

Floors

Drainage

Walls

Ceilings

Heating, Ventilation, and Air-Conditioning (HVAC)

Power and Lighting

Storage Areas

Noise Control

Facilities for Sanitizing Materials

FACILITIES FOR ASEPTIC SURGERY

APPENDIX A: Selected Bibliography

ADMINISTRATION AND MANAGEMENT

ALTERNATIVES

AMPHIBIANS, REPTILES, AND FISHES

ANESTHESIA, PAIN, AND SURGERY

ANIMAL MODELS AND RESOURCES

BIOHAZARDS IN ANIMAL RESEARCH

BIRDS

CATS AND DOGS

DESIGN AND CONSTRUCTION OF ANIMAL FACILITIES

ENRICHMENT

ENVIRONMENTAL CONTAMINANTS

ETHICS

EXOTIC, WILD, AND ZOO ANIMALS

GENERAL REFERENCES

GENETICS AND NOMENCLATURE

LABORATORY ANIMAL CARE

LAWS, REGULATIONS, POLICIES

NONHUMAN PRIMATES

NUTRITION

OTHER ANIMALS

PARASITOLOGY

PATHOLOGY AND CLINICAL PATHOLOGY

PHARMACOLOGY AND THERAPEUTICS

RODENTS AND RABBITS

SAMPLE SIZE AND EXPERIMENTAL DESIGN

SERIAL PUBLICATIONS

TECHNICAL AND PROFESSIONAL EDUCATION

WELFARE

APPENDIX B: Selected Organizations Related to Laboratory Animal Science

APPENDIX C: Some Federal Laws Relevant to Animal Care and Use

ANIMAL WELFARE

ENDANGERED SPECIES

APPENDIX D: Public Health Service Policy and Government Principles Regarding the Care and Use of Animals

PUBLIC HEALTH SERVICE POLICY ON HUMANE CARE AND USE OF LABORATORY ANIMALS

PRINCIPLES FOR THE CARE AND USE OF ANIMALS USED IN TESTING, RESEARCH, AND TRAINING

U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training

Index.

Related Publications.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references and index.

ISBN:

1-280-19263-1

9786610192632

0-309-58869-3

0-585-00230-4

OCLC:

647360138