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Enzymology at the membrane interface : intramembrane proteases / edited by Michael H. Gelb.
Holman Biotech Commons - Periodicals QP601 .M49 v.1 (1955)-v.148 (1987), v.150 (1987)-v.224 (1993), v.226 (1993)-v.228 (1993), v.230 (1994)-v.242 (1994), v.244 (1994)-v.253 (1995), v.257 (1996)-v.262 (1995), v.266 (1996)-v.284 (1997), v.286 (1997)-v.305 (1999), v.332 (2001)-v.333 (2001), v.341 (2001)-v.342 (2001) v.120 1986 (cum. index to v.81-94, 96-101) v.140 1988 (cum. index to v.102-119, 121-134) v.175 1990 (cum. index to v.135-139, 141-167) v.199 1993 (cum. index to v.168-174, 176-194) v.229 1995 (cum. index to v.195-198, 200-227) v.265 1996 (cum. index to v.228, 230-262) v.285 1998 (cum. index to v.263, 264, 266-289)
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Chemistry Library - Books QP601 .M49 v.1-v.193,v.195-v.207,v.209-v.220,v.222-v.228,v.230-v.259,v.261-v.263,v.265-v.285 v.286-v.365,v.367,v.369-v.654,v.656,v.658-v.720,v.722-v.724 v.168/174,176/194-v.195/198,200/227
Available
LIBRA QP601 .M49 v.584
Available from offsite location
LIBRA QP601 .M49 v.1-v.217, v.219-v.220, v.222-v.288, v.291, v.299, v.303 v.306 (2000)-v.321 (2000) v.323 (2000)-v.331 (2001), v.334 (2001)-v.340 (2001), v.343 (2002)-v.390 (2004) v.320 2000 (cum. index to v.290-319) v.355 2002 (cum. index to v.321-354)
Mixed Availability
- Format:
- Book
- Series:
- Methods in enzymology ; 0076-6879 v. 584.
- Methods in enzymology, 0076-6879 ; volume 584
- Language:
- English
- Subjects (All):
- Enzymology.
- Membranes (Biology).
- Biological interfaces.
- Cell membranes.
- Biological transport.
- Enzyme kinetics.
- Cell Membrane--enzymology.
- Membranes--enzymology.
- Proteolysis.
- Medical Subjects:
- Cell Membrane--enzymology.
- Membranes--enzymology.
- Proteolysis.
- Physical Description:
- xix, 474 pages : illustrations (some color); 24 cm.
- Edition:
- First edition.
- Place of Publication:
- Cambridge, MA : Elsevier/Academic Press, 2017.
- Summary:
- Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes. Volume 584 focuses on proteolytic enzymes that access their transmembrane peptide substrates in the membrane phase (interfacial proteases). Biochemical characterization of bacterial and eukaryotic transmembrane proteases are also covered, as well as, kinetic studies including substrate specificity and inhibition. Also discussed are studies that probe the structure of transmembrane proteases, and production of recombinant transmembrane proteases.
- Contents:
- 1. Biochemical Characterization of Function and Structure of RseP, an Escherichia coli S2P Protease / Y. Hizukuri, K. Akiyama, Y. Akiyama
- 2. Signal Peptidase Enzymology and Substrate Specificity Profiling / R.E. Dalbey, D. Pei, Ö.D. Ekici
- 3. Screening and Characterization Strategies for Nanobodies Targeting Membrane Proteins / S. Veugelen, M. Dewilde, B. De Strooper, L. Chávez-Gutiérrez
- 4. Probing the Activity of Eukaryotic Rhomboid Proteases In Vitro / B. Cordier, M.K. Lemberg
- 5. Expression, Purification, and Enzymatic Characterization of Intramembrane Proteases / R. Zhou, Y. Shi, G. Yang
- 6. Analyzing Amyloid-[beta] Peptide Modulation Profiles and Binding Sites of [gamma]-Secretase Modulators / J. Trambauer, A. Fukumori, B. Kretner, H. Steiner
- 7. Probing the Structure and Function Relationships of Presenilin by Substituted-Cysteine Accessibility Method / T. Tomita
- 8. A New Method to Determine the Transmembrane Conformation of Substrates in Intramembrane Proteolysis by Deep-UV Resonance Raman Spectroscopy / J.W. Cooley, A. Abdine, M. Brown, J. Chavez, B. Lada, R.D. JiJi, I. Ubarretxena-Belandia
- 9. An Inducible Reconstitution System for the Real-Time Kinetic Analysis of Protease Activity and Inhibition Inside the Membrane / R.P. Baker, S. Urban
- 10. Production of Recombinant Rhomboid Proteases / E. Arutyunova, R. Panigrahi, K. Strisovsky, M.J. Lemieux
- 11. Mechanism and Inhibition of Rhomboid Proteases / K. Strisovsky
- 12. Enzymatic Assays for Studying Intramembrane Proteolysis / D.M. Bolduc, D.J. Selkoe, M.S. Wolfe
- 13. Methods for Structural and Functional Analyses of Intramembrane Prenyltransferases in the UbiA Superfamily / Y. Yang, N. Ke, S. Liu, W. Li
- 14. Functional Study of the Vitamin K Cycle Enzymes in Live Cells / J.-K. Tie, D.W. Stafford
- 15. Activity Assays for Rhomboid Proteases / E. Arutyunova, K. Strisovsky, M.J. Lemieux.
- Notes:
- Includes bibliographical references and indexes.
- ISBN:
- 9780128122136
- 0128122137
- OCLC:
- 971061428
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