AMP-activated Protein Kinase / edited by Mario D. Cordero, Benoit Viollet.

Format:

Book

Contributor:

Cordero, Mario D., editor.

Viollet, Benoit, editor.

SpringerLink (Online service)

Series:

Experientia. Supplementum 1023-294X ; 107.

Experientia Supplementum, 1023-294X ; 107

Language:

English

Subjects (All):

Medicine.

Human physiology.

Metabolism--Disorders.

Metabolism.

Clinical biochemistry.

Physical Description:

1 online resource.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes. This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease. .

Contents:

Part I: AMPK in health

Structure and Regulation of AMPK

AMPK Regulation of Carbohydrate Metabolism

AMPK Regulation of Lipid Metabolism

AMPK Regulation of Protein Metabolism

AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics

AMPK Regulation of immunology

AMPK and Stem Cells

Part II: AMPK in the diseases

AMPK in metabolic diseases

AMPK in neurodegenerative diseases

AMPK in cardiovascular diseases

AMPK in cancer

AMPK in aging

AMPK in musculoskeletal diseases and pain

AMPK in pathogens

Part III: Pharmacology of AMPK

Metformin, new drugs and AMPK

Small molecules and AMPK

Nutraceutical compounds and AMPK

Part IV: Methods of study in AMPK

Animal models

In vitro study methods.

Other Format:

Printed edition:

ISBN:

9783319435893

Access Restriction:

Restricted for use by site license.