Parental Obesity: Intergenerational Programming and Consequences / edited by Lucy R. Green, Robert L. Hester.

Format:

Book

Contributor:

Green, Lucy R., editor.

Hester, Robert L., editor.

SpringerLink (Online service)

Series:

Physiology in health and disease

Physiology in Health and Disease

Language:

English

Subjects (All):

Medicine.

Gene expression.

Human physiology.

Health promotion.

Maternal and child health services.

Physiology.

Physical Description:

1 online resource.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

In this book, leading figures in the field of Developmental Origins of Health and Disease provide up-to-date information from human clinical trials, cohorts, and animal physiology experiments to reveal the interdependence between parental obesity and health of the offspring. Obesity of the mother and father produces obesity in their offspring, so we are caught up in an intergenerational cycle, which means that even our children's future health is in peril. This book gives a timely and much-needed synthesis of the mechanisms, potential targets of future interventions, and the challenges that need to be overcome in order to break the intergenerational cycle of obesity. This has profound implications for the way in which scientific, clinical and health policy activities are to be directed in order to combat the so-called epidemic of obesity, as well as diabetes, cancer and cardiovascular disease. The book will be of interest to students, clinicians, researchers and health policy makers who are either seeking an introduction to the area of Developmental Origins of Health and Disease or have a specific interest in the pathogenesis of obesity.

Contents:

Why Obesity in Parents Matters

Maternal obesity during pregnancy and cardio-metabolic development in the offspring

Maternal obesity and gestational weight gain as determinants of long-term health

Young maternal age, body composition and gestational intake impact pregnancy outcome: translational perspectives

Maternal obesity and programming of the early embryo

Paternal Obesity and Programming of Offspring Health

The impact of maternal obesity and weight loss during the periconceptional period on offspring metabolism

Mechanisms linking maternal obesity to offspring metabolic health

The effect of maternal overnutrition on reward and anxiety in offspring

The Implications of Maternal Obesity on Offspring Physiology and Behavior in the Non-human Primate

The Impact of Maternal Obesity on Offspring Obesity via Programmed Adipogenesis and Appetite

Developmental programming of non-alcoholic fatty liver disease (NAFLD)

Maternal Metabolic State and Cancer Risk: An Evolving Manifestation of Generational Impact

The influence of maternal obesity on offspring cardiovascular control and insights from rodent models

Maternal obesity effects on the risk of allergic diseases in offspring

Epigenetic mechanisms of maternal obesity effects on the descendants

Early microbe contact in defining child metabolic health and obesity risk.

Other Format:

Printed edition:

ISBN:

9781493963867

Access Restriction:

Restricted for use by site license.