IgG4-Related Kidney Disease / edited by Takao Saito, John H. Stone, Hitoshi Nakashima, Takako Saeki, Mitsuhiro Kawano.

Format:

Book

Contributor:

Saito, Takao, 1946- editor.

Stone, John H., editor.

Nakashima, Hitoshi (Nephrologist), editor.

Saeki, Takako, editor.

Kawano, Mitsuhiro, editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Immunology.

Nephrology.

Rheumatology.

Medicine & Public Health.

Local Subjects:

Medicine & Public Health.

Nephrology.

Rheumatology.

Immunology.

Physical Description:

1 online resource

Contained In:

Springer eBooks

Place of Publication:

Tokyo : Springer Japan : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

Contents:

Part I. General Remarks

1. IgG4-Related Disease: History and Overview

2. IgG4-Related Disease: Pathological Features and Differential Diagnosis

3. Potential Pathways in The Pathogenesis of IgG4-Related Disease

4. Does IgG4-Related Disease Have an Autoimmune Basis?

5. Plasmablasts: A Promising Biomarker in IgG4-RD

Part II. Features of IgG4-Related Ridney Disease and Associated Conditions

6. Overview of IgG4-Related Kidney Disease

7. IgG4-Related Kidney Disease: Clinical and Laboratory Features

8. Imaging Findings

9. Characteristic Tubulointerstitial Nephritis in IgG4-Related Kidney Disease

10. Electron Microscopic Findings

11. IgG4-RelatedKidney Disease: Pathological Features -Membranous Glomerulonephritis

12. IgG4-RelatedKidney Disease: Pathological Features -Other Glomerular Disease

13. IgG4-Related kKidney Diseases and Conditions: Renal Pelvic and Ureteral Diseases

14. Retroperitoneal Fibrosis/Periaortitis and Hydronephrosis

15. Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.)

16. Characteristic Distribution of Inflammatory Lesions in IgG4-Related Kidney Disease: Findings from Autopsy Case Series

17. Diagnosis of IgG4-Related Kidney Disease

18. Pathogenesis of IgG4-Related Kidney Disease

Part III. Treatment of IgG4-RD and IgG4-RKD

19. Corticosteroid Therapy for IgG4-Related Kidney Disease

20. Targeting the B Cell Lineage in IgG4-Related Disease

Part IV. Differential Diagnosis of IgG4-RKD

21. Differential Diagnosis of IgG4-Related Tubulointerstitial Nephritis -An Overview

22. Differential Diagnosis (1): ANCA Associated Vasculitis

23. Differential Diagnosis (2): Castleman Disease

24. Differential Diagnosis (3): Sjögren Syndrome

25. Differential Diagnosis: Lupus Nephritis and IgG4-Related Kidney Disease

Part V. Lessons from Cases

26. Multicentric Castleman's Disease Mimicking IgG4-Related Disease; A Case Report

27. A Case of Concurrent IgG4-Related Kidney Disease and Lupus Nephritis.

Other Format:

Printed edition:

ISBN:

9784431556879

Access Restriction:

Restricted for use by site license.