Antibiotics and antibiotic resistance / edited by Lynn L. Silver, LL Silver Consulting, LLC, Karen Bush, Indiana University.

Format:

Book

Contributor:

Silver, Lynn L., editor.

Bush, Karen (Biologist), editor.

Series:

Cold Spring Harbor perspectives in medicine

Language:

English

Subjects (All):

Antibiotics.

Drug resistance in microorganisms.

MEDICAL--Infectious Diseases.

SCIENCE--Life Sciences--Biology--Microbiology.

MEDICAL--Microbiology.

Drug Resistance, Microbial.

Medical Subjects:

Drug Resistance, Microbial.

Local Subjects:

MEDICAL--Infectious Diseases.

SCIENCE--Life Sciences--Biology--Microbiology.

MEDICAL--Microbiology.

Antibiotics.

Drug resistance in microorganisms.

Physical Description:

xi, 404 pages : illustrations ; 26 cm.

Place of Publication:

Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2016]

Summary:

"Resistance to antibiotics is a growing problem. This book examines the variety of different way antibiotics kill bacteria and the mechanisms bacteria develop that allow them to become resistant. Highlights include: - The Prehistory of Antibiotic Resistance - Bacterial Protein Synthesis as a Target for Antibiotic Inhibition - Tetracycline Antibiotics and Resistance - Antibacterials Developed to Target a Single Organism "-- Provided by publisher.

"Resistance to antibiotics is a growing problem. This book examines the variety of different ways antibiotics kill bacteria and the mechanisms bacteria develop that allow them to become resistant"-- Provided by publisher.

Contents:

Machine generated contents note:

(preliminary)

Preface

1. The Whys and Wherefores of Antibiotic Resistance

C.R. Strachan and Julien Davies

2. The Prehistory of Antibiotic Resistance

Julie Perry, Nicholas Waglechner, and Gerard Wright

5. ss-Lactam Resistance Mechanisms: Gram-Positive Bacteria

Jed F. Fisher and Shahriar Mobashery

12. Polymyxin: Alternative Mechanisms of Action and Resistance

Michael J. Trimble, Patrik Mlynárcik, Milan Kolár, and Robert E.W. Hancock

13. Resistance Mechanisms and the Future of the Bacterial Enoyl-Acyl Carrier Protein Reductase (Fabl) Antibiotics

Jiangwei Yao and Charles O. Rock

14. Antibacterial Drug Discover Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC

Alice L. Erwin

15. Topoisomerase Inhibitors: Fluoroquinolone Mechanisms of Action and Resistance

David C. Hooper and George A. Jacoby

19. Bacterial Protein Synthesis as a Target for Antibiotic Inhibition

Stefan Arenz and Daniel N. Wilson

20. Aminoglycosides: An Overview

Kevin M. Krause, Alisa W. Serio, Timothy R. Kane, and Lynn E. Connolly

21. Tetracycline Antibiotics and Resistance

Trudy H. Grossman

23. Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance

Stefan Schwarz, Jianzhong Shen, Kristina Kadlec, Yang Wang, Geovana Brenner Michael, Andrea T. Fessler, and Birte Vester

26. Antibacterials Developed to Target a Single Organism: Mechanisms and Frequencies of Reduced Susceptibility to the Novel Anti-Clostridium difficile Compound Fidaxomicin and LFF571

Jennifer A. Leeds

27. Fusidic Acid

A Bacterial Elongation Factor Inhibitor for the Oral Treatment of Acute and Chronic Staphylococcal Infections

Prabhavathi Fernandes

Index.

Notes:

Includes bibliographical references and index.

ISBN:

9781621821199

1621821196

OCLC:

922914047