Handbook for clinical trials of imaging and image-guided interventions / edited by Nancy A. Obuchowski and G. Scott Gazelle.

Format:

Book

Contributor:

Obuchowski, Nancy A., editor.

Gazelle, G. Scott, editor.

Wiley InterScience (Online service)

President Emeritus Martin Meyerson Fund.

Language:

English

Subjects (All):

Clinical Trials as Topic.

Diagnostic Imaging.

Radiotherapy.

Surgery, Computer-Assisted.

Diagnostic imaging.

Clinical trials.

Medical Subjects:

Clinical Trials as Topic.

Diagnostic Imaging.

Radiotherapy.

Surgery, Computer-Assisted.

Physical Description:

1 online resource (vii, 215 pages)

Place of Publication:

Hoboken, New Jersey : John Wiley & Sons, Inc., [2016]

System Details:

text file

Summary:

Handbook for Clinical Trials of Imaging and Image-Guided Interventions, Handbook for Clinical Trials of Imaging and Image-Guided Interventions is the first single-source, multi-disciplinary reference based on the didactic sessions presented at the annual "Clinical Trials Methodology Workshop" for radiologists, radiation oncologists, and imaging scientists (sponsored by the Radiological Society of North America (RSNA)). It focuses on educating radiologists, radiation oncologists, and those involved in imaging research with how to design and conduct clinical trials to evaluate imaging technology and imaging biomarkers. The internationally renowned contributors take a broad approach, starting with principles of technology assessment and then move into specific topics covering the clinical trials of therapy and clinical research in imaging-guided interventions including radiotherapy. They discuss the use of imaging as a predictor of therapeutic response, screening trial design, and the practicalities of how to run an efficient clinical trial and good working practices. Later chapters provide a comprehensive array of quantitative methods including an introduction to statistical considerations in study design, biostatistical analysis methods and their role in clinical imaging research, methods for quantitative imaging biomarker studies, and an introduction to cost effectiveness analysis. Handbook for Clinical Trials of Imaging and Image-Guided Interventions will educate and prepare radiologists at all levels and in all capacities in planning and conducting clinical imaging trials. Book jacket.

Contents:

Imaging technology assessment / Pari V. Pandharipande, G. Scott Gazelle

Clinical trials of therapy / Sayeh Lavasani, Ali Mahinbakht, Anthony F. Shields

Clinical trials of image guided interventions including radiotherapy studies / Gary S. Dorfman, Stephen M. Hahn

Imaging as predictor of therapeutic response / David A. Mankoff, Anthony F. Shields

Screening trials and design / Constance D. Lehman, Diana L. Miglioretti

Practicalities of running a trial / Michael T. Lu, Elizabeth C. Adami, Udo Hoffmann

Statistical issues in study design / Nancy A. Obuchowski

Introduction to biostatistical methods / Diana L. Miglioretti, Todd A. Alonzo, Nancy A. Obuchowski

Methods of studies of diagnostic tests / Jeffrey D. Blume

Methods for quantitative imaging biomarker studies / Alicia Y. Toledano, Nancy A. Obuchowski

Introduction to cost-effectiveness analysis in clinical trials / Ruth C. Carlos, G. Scott Gazelle.

Notes:

Includes bibliographical references and index.

Electronic reproduction. Hoboken, N.J. Available via World Wide Web.

Description based on online resource; title from digital title page (viewed on September 20, 2016).

Local Notes:

Acquired for the Penn Libraries with assistance from the President Emeritus Martin Meyerson Fund.

Other Format:

Print version: Handbook for clinical trials of imaging and image-guided interventions

ISBN:

9781118849712

111884971X

9781118849569

1118849566

Publisher Number:

99968785641

Access Restriction:

Restricted for use by site license.