The Duration and Safety of Osteoporosis Treatment : Anabolic and Antiresorptive Therapy / edited by Stuart Silverman, Bo Abrahamsen.

Format:

Book

Contributor:

Silverman, Stuart Jay, 1933- editor.

Abrahamsen, Bo, editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Endocrinology.

Orthopedics.

Physical Description:

1 online resource (XVI, 338 pages 100 illustrations, 38 illustrations in color.)

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.

Contents:

Foreword

Preface

Osteoporosis: Pathophysiology & Epidemiology

Antiresorptives

Anabolics

Tools for Assessing Fracture Risk and for Treatment Monitoring

Treatment Failure

Epidemiology of Atypical Subtrochanteric and Femoral Shaft Fractures

Bisphosphonate-Related Atypical Femoral Fractures and Their Radiographic Features

Factors Contributing to Atypical Femoral Fractures

Clinical Presentation of Atypical Femur Fractures

Effects of Antiresorptive Therapy on Bone Microarchitecture

Management of Atypical Femoral Fractures

Osteonecrosis of the Jaw: Clinico-Pathologic and Radiologic Features

Epidemiology of Osteonecrosis of the Jaws from Antiresorptive Treatment

Management of Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Treatment

Long-Term Efficacy and Safety of Treatments for Osteoporosis

Management of Drug Holidays

Patients Who Do Not Take Their Osteoporosis Medications: Can We Help Them Become Compliant?

Fractures and Healing on Antiresorptive Therapy

Antiresorptive Therapy and Mortality and Cancer Incidence

Other Safety Concerns

The Impact of Regulatory and Scientific Organizations Recommendations on Clinical Decision Making

Integrated Clinical View on Long-Term Management of Patients with Osteoporosis

Conclusions.

Other Format:

Printed edition:

ISBN:

9783319236391

Access Restriction:

Restricted for use by site license.