Cardiovascular Imaging : Arterial and Aortic Valve Inflammation and Calcification / edited by Elena Aikawa.

Format:

Book

Contributor:

Aikawa, Elena, editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Radiology.

Nuclear medicine.

Cardiology.

Physical Description:

1 online resource

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2015.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound, and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.

Contents:

Part 1: Preclinical imaging of mechanisms of atherosclerosis and its complications

Pathobiology and basic mechanisms of atherosclerosis

Ultrasound imaging of endothelial cell activation and damage in atherosclerosis

Molecular imaging of macrophages

Optical molecular imaging of inflammation and calcification in atherosclerosis

Imaging of antigen-presenting cells

Imaging of oxidation-specific epitopes

Intravascular molecular imaging

Imaging of complications of atherosclerosis (platelets aggregation and thrombosis)

Part 2: Imaging insights into mechanisms of calcific aortic valve disease (CAVD) and calcification

Pathobiology and basic mechanisms of CAVD

Molecular imaging of aortic valve inflammation and calcification: Preclinical studies

PET CT imaging of inflammation and calcification in CAVD: Clinical studies

Ultrasound imaging of CAVD

Micro-OCT imaging of microcalcification

Part 3: Clinical imaging of inflammation and calcification

MR imaging in cardiovascular disease

Molecular mechanisms of atherosclerosis imaged by MR

Cardiovascular nuclear imaging

Preclinical and clinical PET CT imaging of inflammation and calcification

Clinical feasibility and monitoring of the effects of anti-inflammatory therapy in atherosclerosis.

Other Format:

Printed edition:

ISBN:

9783319092683

Access Restriction:

Restricted for use by site license.