General Methods in Biomarker Research and their Applications / edited by Victor R. Preedy, Vinood B. Patel.

Format:

Book

Contributor:

Preedy, Victor R., editor.

Patel, Vinood B., editor.

SpringerLink (Online service)

Series:

Biomarkers in Disease: Methods, Discoveries and Applications,. 2451-9766

Biomarkers in Disease: Methods, Discoveries and Applications, 2451-9766

Language:

English

Subjects (All):

Medicine.

Cancer--Research.

Cancer.

Pharmacology.

Oncology.

Physical Description:

1 online resource.

Contained In:

Springer eBooks

Place of Publication:

Dordrecht : Springer Netherlands : Imprint: Springer, 2015.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists.

Contents:

Biomarker for Amyotrophic Lateral Sclerosis (Motor Neurone Disease)

Biomarkers and their applications to toxicology and toxicogenomics

Biomarkers for Depression

Biomarkers in Chronic Obstructive Pulmonary Disease (COPD): Current Concerns and Future Prospects

Biomarkers in Urine and Use of Creatinine

Biomarkers of Graft-Versus-Host Disease

Biomarkers of Menopause

Biomarkers of Parkinson's Disease

Biomarkers of Vector Bites

Biomarkers of the menopause.- Chronic Heart Failure and Serum Collagen

FABP3 as biomarkers

Fetal Membrane Biomarkers.- Flow Cytometry as Platform for Biomarker Evaluation

Formalin-fixed paraffin-embedded tissue (FFPET) sections for biomarker discovery

Glycomics as biomarkers

Inflammasome Proteins as Biomarkers of Injury and Disease

Isoprostanes as biomarkers of disease and early biological effect.-Mass spectrometry for biomarker discovery

Micro RNA as Biomarker for Brain Injury

MIP-1alpha as biomarker

Natriuretic Peptides for Diagnosis, Prognosis and Management of Heart Failure

OMICS-based approaches to biomarker discovery and challenges of subsequent validation

Pediatric biomarkers after cardac surgery

Pentraxin 3 as Biomarker

Pfetin: Novel prognostic biomarker

Plasma galectin-3 as biomarker

S100B as a Biomarker

Salivary amylase as a stress biomarker

Seasonal allergic rhinitis and systems biology-oriented biomarker discovery

Serum Heat Shock Proteins as Novel Biomarker for Heart Failure

Urinary Biomarkers of Environmental Health: Jet Fuel

YKL-40 as Biomarker: Focus on Cardiovascular Disease.

Other Format:

Printed edition:

ISBN:

9789400776968

Access Restriction:

Restricted for use by site license.