Studies on Hepatic Disorders / edited by Emanuele Albano, Maurizio Parola.

Format:

Book

Contributor:

Albano, E., editor.

Parola, Maurizio, editor.

SpringerLink (Online service)

Series:

Oxidative stress in applied basic research and clinical practice 2197-7224

Oxidative Stress in Applied Basic Research and Clinical Practice, 2197-7224

Language:

English

Subjects (All):

Life sciences.

Hepatology.

Oxidative stress.

Physical Description:

1 online resource.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Humana Press, 2015.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

This volume examines the impact of free radical biology on hepatic disorders such as viral hepatitis, alcoholic disease, iron overload, and Wilson's disease. It thoroughly explores the role of oxidative stress in acute and chronic disease, addressing factors such as redox biomarkers; antioxidant defense and protection; cell signaling; mutations; oxidative damage involving lipids, proteins, and nucleic acids; membrane trafficking; inflammation; mitochondrial dysfunction; alterations in immunological function; toxicology; and hypoxia. Its four sections, consisting of chapters by recognized field leaders, deal with basic principles of oxidation and hepatology, oxidative stress-related pathophysiology, oxidative stress and liver disease, and liver cancer. Intuitively structured and comprehensive, Studies on Hepatic Disorders is an invaluable addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series and an essential resource for clinical hepatologists and researchers interested in the role of oxidative stress on liver function and disease.

Contents:

Part 1: Oxidative Stress: Basic Principles in the Liver Scenario

Principles of Redox Signaling

Oxidative Stress, Antioxidant Defenses and the Liver

Oxidative Mechanisms in Liver Senescence and Regeneration

Part 2: Oxidative Stress and Liver Pathophysiology: From Cell Damage and Death to Inflammatory and Fibrogenic Responses

Oxidative Stress and Hepatocellular Injury

Oxidative Stress and the Unfolded Protein Response in the Liver

Oxidative Stress and Liver Inflammation

Oxidative Stress and Liver Ischemia-Reperfusion Injury

Oxidative Stress and Liver Fibrogenesis

Part 3: Oxidative Stress in Specific Liver Disease Conditions

Oxidative Stress in Acute Liver Failure

Oxidative Stress in Alcoholic Liver Disease

Oxidative Stress in Chronic Viral Hepatitis

Oxidative Stress in Nonalcoholic Fatty Liver Disease

Oxidative Stress in Non-autoimmune Biliary Diseases

Oxidative Stress in Autoimmune Liver Diseases

Oxidative Stress and Hepatic Iron Overload

Oxidative Stress in the Central Nervous System Complications of Chronic Liver Failure

Oxidative Stress and Liver Transplantation

Antioxidant Approach to the Therapy of Chronic Liver Disease

Part 4: Oxidative Stress and Liver Cancer

Liver Cancer Classification

Oxidative Stress Mechanisms in Hepatocarcinogenesis

The Role of Oxidative Stress in Hepatocarcinogenesis.

Other Format:

Printed edition:

ISBN:

9783319155395

Access Restriction:

Restricted for use by site license.