Translational research in traumatic brain injury / Daniel Laskowitz, Gerald Grant [editors].

Format:

Book

Contributor:

Laskowitz, Daniel, editor.

Grant, Gerald (Gerald A.), editor.

CRC Press.

Gail and Warren Lieberfarb Mental Health and Neuroscience Library Resources Fund.

Series:

Frontiers in neuroscience (Boca Raton, Fla.)

Frontiers in neuroscience

Language:

English

Subjects (All):

Brain Injuries.

Translational Research, Biomedical.

Brain damage--Research.

Brain damage.

Brain damage--Patients--Rehabilitation.

Medical Subjects:

Brain Injuries.

Translational Research, Biomedical.

Physical Description:

1 online resource : illustrations.

polychrome

Place of Publication:

Boca Raton (FL) : CRC Press/Taylor and Francis Group, 2016.

System Details:

text file

Summary:

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury-related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology, Pathophysiology, Diagnosis, Current treatment strategies and sequelae, Future therapies, Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain-injured patient. Book jacket.

Contents:

Epidemiology

Sport-related traumatic brain injury

Diffuse axonal injury

Blood-brain barrier pathophysiology following traumatic brain injury

Cellular and molecular mechanisms of secondary neuronal injury following traumatic brain injury

Neuroinflammation

Neurosteroids and traumatic brain injury : translating biomarkers to therapeutics; overview and pilot investigations in Iraq and Afghanistan era veterans

Neuroplasticity after traumatic brain injury

Genetic influences in traumatic brain injury

Modeling post-traumatic epilepsy for therapy development

Translational principles of neuroprotective and neurorestorative therapy testing in animal models of traumatic brain injury

Biomarkers of traumatic brain injury and their relationship to pathology

Advanced neuroimaging of mild traumatic brain injury

Epilepsy after traumatic brain injury

Intracranial pressure monitoring and management

Post-Traumatic Stress Disorder : relationship to traumatic brain injury and approach to treatment

Traumatic brain injury and potential for neuromodulation

Enhanced functional outcome from traumatic brain injury with brain-machine interface neuromodulation : neuroprosthetic scaling in relation to injury severity

Neurocognitive and psychiatric symptoms following mild traumatic brain injury.

Notes:

Title from table of contents web page.

Includes bibliographical references.

Electronic reproduction. Boca Raton, FL Available via World Wide Web.

Description based on version viewed January 20, 2016.

Local Notes:

Acquired for the Penn Libraries with assistance from the Gail and Warren Lieberfarb Mental Health and Neuroscience Library Resources Fund.

Other Format:

Print version: Laskowitz, Daniel Translational Research in Traumatic Brain Injury

ISBN:

9781466584914

1466584912

9781466584921

1466584920

Publisher Number:

99966148385

Access Restriction:

Restricted for use by site license.