Peripheral Nerve Disorders : Pathology and Genetics.

Format:

Book

Author/Creator:

Vallat, Jean-Michel.

Contributor:

Weis, Joachim, 1960-

ebrary, Inc.

Language:

English

Physical Description:

1 online resource ( 320 pages)

Place of Publication:

Hoboken : Wiley, 2014.

System Details:

text file

Contents:

Peripheral nerve disorders: pathology and genetics; Copyright; Contents; Contributor list; Preface; Abbreviations; Chapter 1 Clinical assessment and classification of peripheral nerve diseases; Pathophysiology; Clinical examination; Pattern of distribution of nerve involvement; Medical history; Clinical presentation; Examination; Electrophysiological examination; Electromyography; Nerve conduction studies; Laboratory investigations in peripheral neuropathies; Clinical classification of peripheral neuropathies; Indications for nerve biopsy; Nerve selection.

Indications for and information from nerve biopsyReferences; Chapter 2 Combined muscle and nerve biopsy; Introduction; Technique; Results; Vasculitis; Intra-vascular lymphoma; Sarcoidosis; Amyloid polyneuropathies; Mitochondrial cytopathies; Storage diseases; Cholesterol emboli; References; Chapter 3 Cutaneous nerve biopsy; Introduction; Technique; Skin biopsy and location; Tissue preparation; Quantification of intra-epidermal nerve fiber density; Results; Morphology of intra-epidermal and dermal nerve fibers; Autonomic innervation.

Examples of the diagnostic value of cutaneous nerve biopsy in peripheral nerve diseaseSmall fiber neuropathy; Diabetic neuropathy; Hereditary neuropathies; Demyelinating and vasculitic neuropathies; Nerve regeneration; Conclusions and recommendations for practical application; References; Chapter 4 Methods for examination of peripheral nerve; General considerations; Nerve biopsy; Postmortem examination; Methods for evaluating nerve biopsies; Routine histology (paraffin embedding); Immunohistochemistry; Plastic-resin embedding; Frozen sections for immunofluorescence.

Dissociation of fibers (nerve teasing)Frozen specimens for molecular analysis; Electron microscopy; Quantitative and morphometric analyses; References; Chapter 5 Complications from nerve biopsy; Introduction: My nerve biopsy; Frequency of complications; When to perform a nerve biopsy; Predicting complications; Reducing complications; References; Chapter 6 Anatomy of the peripheral nerve; Introduction; Normal anatomy of peripheral nerves; The nerve trunk; Axons; Myelinated nerve fibers; Unmyelinated axons; End organs; Sensory endings; Variations according to age; Development; Age changes.

Notes:

Electronic reproduction. Palo Alto, Calif. Available via World Wide Web.

Print version record.

ReferencesChapter 7 Basic pathology of the peripheral nervous system; Introduction; Changes in myelin sheaths; Demyelination and remyelination; Onion bulb formation; Disorders characterized by demyelination; Myelin alterations in axonal disorders; Hypertrophy of myelin sheaths; Other characteristic myelin changes; Alterations of axons; Wallerian degeneration; Developmental disturbances of peripheral neurons; Inherited axonal neuropathies; Intermediate (axonal and demyelinating) forms of neuropathy; Alterations of unmyelinated nerve fibers; Endoneurial connective tissue changes.

Perineurial changes.

Other Format:

Print version: Vallat, Jean-Michel. Peripheral Nerve Disorders : Pathology and Genetics.

ISBN:

9781118618400

1118618408