Transcriptomics and Gene Regulation / edited by Jiaqian Wu.

Format:

Book

Contributor:

Wu, Jiaqian, editor.

SpringerLink (Online service)

Series:

Translational bioinformatics 2213-2775 ; 9.

Translational bioinformatics

Language:

English

Subjects (All):

Life sciences.

Gene expression.

Neurosciences.

Bioinformatics.

Physical Description:

1 online resource.

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Dordrecht : Springer Netherlands : Imprint: Springer, 2016.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expression data integration in complex human diseases etc. The book is particularly useful for researchers and students in the field of molecular biology, clinical biology and bioinformatics, as well as physicians etc. Dr. Jiaqian Wu is assistant professor in the Vivian L. Smith Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Centre, Houston, TX, USA.

Contents:

The Analyses of Global Gene Expression and Transcription Factor Regulation

Global Approaches to Alternative Splicing and its Regulation - Recent Advances and Open Questions

Long Non-coding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System

Gene expression models of signaling pathways

From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases

Introduction to Isoform Sequencing using Pacific Biosciences Technology (Iso-Seq)

Systematic and Integrative Analysis of Gene Expression to Identify Feature Genes Underlying Human Diseases.

Other Format:

Printed edition:

ISBN:

978-94-017-7450-5

9789401774505

Access Restriction:

Restricted for use by site license.