NF-κB-Related Genetic Diseases / by Gilles Courtois, Alessandra Pescatore, Jérémie Gautheron, Francesca Fusco, Matilde Valeria Ursini, Anna Senegas.

Format:

Book

Author/Creator:

Courtois, Gilles, author.

Pescatore, Alessandra, author.

Gautheron, Jérémie, author.

Fusco, Francesca, author.

Ursini, Matilde Valeria, author.

Senegas, Anna, author.

Contributor:

SpringerLink (Online service)

Series:

SpringerBriefs in biochemistry and molecular biology 2211-9353

SpringerBriefs in Biochemistry and Molecular Biology, 2211-9353

Language:

English

Subjects (All):

Medicine.

Human genetics.

Molecular biology.

Clinical biochemistry.

Physical Description:

1 online resource.

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2016.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans, complementing studies performed with mouse models. In addition, people treating those patients acquire a deeper understanding of the molecular basis of the pathophysiological processes.

Contents:

1) The NF-kB signaling pathways: players and Functions

2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation

3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation

4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling

5)Lessons Learned from Studying NF-kB Related Genetic Diseases.

Other Format:

Printed edition:

ISBN:

978-3-319-25850-8

9783319258508

Access Restriction:

Restricted for use by site license.