Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry / edited by Rainer Cramer.

Format:

Book

Contributor:

Cramer, Rainer, editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Life sciences.

Mass spectrometry.

Biotechnology.

Microbiology.

Proteomics.

Proteins.

Physical Description:

1 online resource

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2016.

System Details:

Mode of Access: World Wide Web.

text file PDF

Summary:

This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation; large-scale, high-speed MS sample profiling; new methods based on MALDI or MALDI-like sample preparations; and the advantages of MALDI MS analysis over ESI (electrospray ionization). This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: · Showcases new techniques and applications in MALDI MS · Demonstrates how MALDI is preferable to ESI · Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and various application areas, such as cancer proteomics.

Contents:

Employing 'second generation' matrices

(MA)LDI MS mass spectrometry imaging at high specificity and sensitivity

Techniques for fingermark analysis using MALDI MS - a practical overview

Whole/Intact Cell MALDI MS Biotyping in Mammalian Cell Analyis

MALDI biotyping for microorganism identification in clinical microbiology

Future applications of MALDI-TOF MS in microbiology

MALDESI: Fundamentals, direct analysis, and MS imaging

Microprobe MS Imaging of Live Tissues, Cells, and Bacterial Colonies using LAESI

Efficient production of multiply charged MALDI ions

Food Authentication by MALDI MS - MALDI-TOF MS Analysis of Fish Species

Quantitative MALDI MS using Ionic Liquid Matrices

Disease profiling by MALDI MS analysis of biofluids

Ionic Liquids and other liquid matrices for sensitive MALDI MS analysis

Coupling liquid MALDI MS to liquid chromatography.

Other Format:

Printed edition:

ISBN:

978-3-319-04819-2

9783319048192

Access Restriction:

Restricted for use by site license.