Immunity / William E. Paul.

Format:

Book

Author/Creator:

Paul, William E., author.

Contributor:

EBSCOhost

Patrick B. and Anne Gaydosh Hughes Memorial Book Fund.

Language:

English

Subjects (All):

Immunity.

Immune system.

Immunologic diseases.

Immune System Diseases--immunology.

Immune System Phenomena.

Medical Subjects:

Immune System Diseases--immunology.

Immunity.

Immune System Phenomena.

Physical Description:

1 online resource

polychrome

Place of Publication:

Baltimore : Johns Hopkins University Press, 2015.

System Details:

text file

Contents:

Part 1 Immunology

1 Defense and Danger 3

2 Tracing an Immune Response 14

3 The Laws of Immunology: Universality, Tolerance, and Appropriateness 20

4 Growing Up and Learning Immunology 29

Part 2 The First Law: Universality

5 Vaccines and Serum Therapy 39

6 How Is Specificity Achieved? 43

7 Immunology's "Eureka": Clonal Selection 58

8 How Does Each Lymphocyte Develop a Distinct Receptor? 72

9 B Cells and T Cells Recognize Different Types of Antigens 82

10 My Foray into the Specificity Problem 88

11 Genes and Immune Responses 93

12 The Laboratory of Immunology and the T-Cell Receptor 101

Part 3 The Second Law: Tolerance

13 What Is Tolerance? 107

14 How Does Tolerance Develop? 114

15 Regulatory T Cells and the Prevention of Autoimmunity 118

Part 4 The Third Law: Appropriateness

16 Different Structures, Different Functions 129

17 Specific Types of Infections, Specific Types of T-Cell Responses 137

18 Our Discovery of IL-4 and the Cells That Make It 140

19 CD8 T Cells: Killer Cells and Friends 144

20 Dendritic Cells: The Cells That Interpret the Infectious Threat 149

Part 5 How Did the Immune System Evolve?

21 An "Ancient" Immune Response Controls "Modern" Immunity 155

22 The Microbiome and Innate Immunity 168

23 Evolution of the Immune System and Innate Lymphoid Cells 173

Part 6 AIDS, Autoimmunity, Allergy, Cancer, and Transplantation

24 The HIV Epidemic and the Office of AIDS Research 183

25 How the Immune System Causes Rheumatoid Arthritis and Lupus 192

26 Allergy and Asthma 201

27 InterIeukin-4 and Allergy 205

28 Can the Immune System Control Cancer? 208

29 New Parts for Old: Bone Marrow and Organ Transplantation 215

30 Julien 222.

Notes:

Includes bibliographical references and index.

Electronic reproduction. Ipswich, MA Available via World Wide Web.

Description based on online resource; title from digital title page (viewed on September 29, 2015).

Local Notes:

Acquired for the Penn Libraries with assistance from the Patrick B. and Anne Gaydosh Hughes Memorial Book Fund.

Other Format:

Print version: Paul, William E., author. Immunity

ISBN:

9781421418025

1421418029

Publisher Number:

99964354086

Access Restriction:

Restricted for use by site license.