Epigenetics : current research and emerging trends / edited by Brian P. Chadwick.

Format:

Book

Contributor:

Chadwick, Brian, editor.

EBSCOhost.

Rosengarten Family Fund.

Language:

English

Subjects (All):

Epigenesis.

Genetic regulation.

Physical Description:

1 online resource

polychrome

Place of Publication:

Norfolk, UK : Caister Academic Press, [2015]

System Details:

text file

Summary:

Epigenetics can have a significant impact on human health and disease susceptibility. Over the past few years, significant progress has occurred in this rapidly advancing field, and much key research has been published. This editor of this book has gathered together pioneers in the field of epigenetics to produce a volume of thought-provoking discussions on classic aspects of epigenetics and on the newer emerging areas. The 17 chapters includes topics on the impact of metabolism on the epigenome, how our actions may impact the health of our offspring several generations removed, and how exposure to environmental toxicans can have long-lasting effects on our epigenome with devastating consequences. This up-to-date volume is a major resource essential for those working in the field and is recommended reading for anyone new to this fascinating and fast-moving area of research. Book jacket.

Contents:

1 The Multifaceted Roles of YY1 in the Establishment of the Cellular Epigenetic Landscape / Raed Rizkallah Rizkallah, Raed 1

2 SETting up the Epigenome Through the Histone Methyltransferase SETDB1 / Zhuo Sun Sun, Zhuo, Brian P. Chadwick Chadwick, Brian P. 23

3 Sirtuin Deacetylases in Fungi: Connecting Metabolism to Lifecycle Progression, Stress Response and Genome Stability / Laura N. Rusche Rusche, Laura N., Ashleigh S. Hanner Hanner, Ashleigh S., Justin M.H. Heltzel Heltzel, Justin M.H., Kristen M. Humphrey Humphrey, Kristen M., Shivali Kapoor Kapoor, Shivali, Christopher B. Rupert Rupert, Christopher B. 53

4 Development-linked Differences in Cytosine 5-Hydroxymethylation in Mammalian DNA: Relationship to 5-Methylcytosine and Function / Melanie Ehrlich Ehrlich, Melanie, Michelle Lacey Lacey, Michelle, Guoqiang Zhang Zhang, Guoqiang, Kenneth C. Ehrlich Ehrlich, Kenneth C., Sriharsa Pradhan Pradhan, Sriharsa 77

5 The Identification of Mammalian Proteins Involved in Epigenetics / Luke Isbel Isbel, Luke, Harry Oey Oey, Harry, Emma Whitelaw Whitelaw, Emma 105

6 Chromatin-mediated Response to Stimuli / Daniel L. Vera Vera, Daniel L., Lauren A. Cole Cole, Lauren A., Benjamin Hoffman Hoffman, Benjamin, Jonathan H. Dennis Dennis, Jonathan H. 125

7 The Epigenetics of Centromere Function / Justyne E. Ross Ross, Justyne E., Shannon M. McNulty McNulty, Shannon M., Beth A. Sullivan Sullivan, Beth A. 133

8 Dosage Compensation in Frogs and Toads / John H. Malone Malone, John H. 167

9 Ingenious Genes: The Diverse Roles of Long Non-coding RNA in Regulatory Processes / Emily M. Darrow Darrow, Emily M., Brian P. Chadwick Chadwick, Brian P. 185

10 Epigenetic Mechanisms in Rett Syndrome / Janine M. LaSalle LaSalle, Janine M. 199

11 The Long and Short of Facioscapulohumeral Muscular Dystrophy / Sunny Das Das, Sunny, Brian P. Chadwick Chadwick, Brian P. 217

12 The Epigenetics of Nuclear Reprogramming to Pluripotency / Theodore P. Rasmussen Rasmussen, Theodore P. 255

13 Emerging Role of the Guanine-quadruplex DNA Secondary Structure in Epigenetics / Aradhita Baral Baral, Aradhita, Dhurjhoti Saha Saha, Dhurjhoti, Shantanu Chowdhury Chowdhury, Shantanu 271

14 Clinical Epigenetics in Cancer / María G. Garcia Garcia, María G., Estela G. Toraño Toraño, Estela G., Agustin F. Fernández Fernández, Agustin F., Mario F. Fraga Fraga, Mario F. 285

15 Environment and the Epigenetic Transgenerational Inheritance of Disease / Ingrid Sadler-Riggleman Sadler-Riggleman, Ingrid, Michael K. Skinner Skinner, Michael K. 297

16 Metabolic Inputs into Epigenetics / Scott J. Bultman Bultman, Scott J. 307

17 Environmental Exposures: Impact on the Epigenome / Jaclyn M. Goodrich Goodrich, Jaclyn M., Dana C. Dolinoy Dolinoy, Dana C. 327.

Notes:

Includes bibliographical references and index.

Electronic reproduction. Ipswich, MA Available via World Wide Web.

Description based on online resource; title from digital title page (viewed on June 04, 2015).

Local Notes:

Acquired for the Penn Libraries with assistance from the Rosengarten Family Fund.

ISBN:

9781910190081

191019008X

Publisher Number:

99963821053

Access Restriction:

Restricted for use by site license.